Evidence map›Paper›PMID 35003140›Full record

ArticleFrontiers in immunology2021

Development of an

Patrick J Madden, Muhammad S Arif, Mark E Becker, Michael D McRaven, Ann M Carias, Ramon Lorenzo-Redondo, Sixia Xiao, Cecily C Midkiff, Robert V Blair, Elizabeth Lake Potter and 12 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 8 institutions in 1 country.

Patrick J MaddenDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Muhammad S ArifDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Mark E BeckerDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Michael D McRavenDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Ann M CariasDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Ramon Lorenzo-RedondoDepartment of Medicine, Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Sixia XiaoDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Cecily C MidkiffDivision of Comparative Pathology, Tulane National Primate Research Center, Covington, LA, United States.
Robert V BlairDivision of Comparative Pathology, Tulane National Primate Research Center, Covington, LA, United States.
Elizabeth Lake PotterVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Laura Martin-SanchoImmunity and Pathogenesis Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Alan DodsonBioqual Inc., Rockville, MD, United States.
Elena MartinelliDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
John-Paul M ToddVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Francois J VillingerNew Iberia Research Center, University of Louisiana-Lafayette, New Iberia, LA, United States.
Sumit K ChandaImmunity and Pathogenesis Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Pyone Pyone AyeDivision of Comparative Pathology, Tulane National Primate Research Center, Covington, LA, United States.
Chad J RoyDivision of Microbiology, Tulane National Primate Research Center, Covington, LA, United States.
Mario RoedererVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Mark G LewisBioqual Inc., Rockville, MD, United States.
Ronald S VeazeyDivision of Comparative Pathology, Tulane National Primate Research Center, Covington, LA, United States.
Thomas J HopeDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Northwestern University · USTulane University · USBioqual · USNational Institute of Allergy and Infectious Diseases · USDiscovery Institute · USNational Institutes of Health · USSanford Burnham Prebys Medical Discovery Institute · USUniversity of Louisiana at Lafayette · US

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
Identification of the Initial Targets of Transmission R37AI094595 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Thomas Hope · 2017 to 2026
$10.0M
Understanding the mechanism(s) of systemic antibody delivery, distribution, and localization to mucosal sites in the in vivo macaque modelK01OD026571 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CARIAS, ANN M · 2018 to 2020
$1.1M
NIAID NIH HHS R37 AI094595NIH HHS K01 OD026571NIH HHS P51 OD011104
6 · The paper itself

Abstract

Infection with the novel coronavirus, SARS-CoV-2, results in pneumonia and other respiratory symptoms as well as pathologies at diverse anatomical sites. An outstanding question is whether these diverse pathologies are due to replication of the virus in these anatomical compartments and how and when the virus reaches those sites. To answer these outstanding questions and study the spatiotemporal dynamics of SARS-CoV-2 infection a method for tracking viral spread

Indexed as

AnimalsAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralCell LineCOVID-19Disease Models, AnimalFluorescent Antibody TechniqueHumansLungMacaca mulattaProof of Concept StudySARS-CoV-2Spike Glycoprotein, CoronavirusViral LoadVirus ReplicationAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralCR3022Spike Glycoprotein, Coronavirusspike protein, SARS-CoV-2antibodiesantibody probesCOVID-19nonhuman primatesrhesus macaqueSARS-CoV-2

Identifiers

PMID35003140
PMCPMC8739270
OpenAlexW4200079848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.