Evidence map›Paper›PMID 35003122›Full record

ArticleFrontiers in immunology2021

Efficient

Sabrina B Bennstein, Sandra Weinhold, Özer Degistirici, Robert A J Oostendorp, Katharina Raba, Gesine Kögler, Roland Meisel, Lutz Walter, Markus Uhrberg

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. ILC3: a case of conflicted identity.Frontiers in immunology · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sabrina B BennsteinInstitute for Transplantation Diagnostics and Cell Therapeutics, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Sandra WeinholdInstitute for Transplantation Diagnostics and Cell Therapeutics, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Özer DegistiriciDivision of Pediatric Stem Cell Therapy, Clinic for Pediatric Oncology, Hematology and Clinical Immunology, Center for Children and Adolescence Health, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Robert A J OostendorpTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.
Katharina RabaInstitute for Transplantation Diagnostics and Cell Therapeutics, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Gesine KöglerInstitute for Transplantation Diagnostics and Cell Therapeutics, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Roland MeiselDivision of Pediatric Stem Cell Therapy, Clinic for Pediatric Oncology, Hematology and Clinical Immunology, Center for Children and Adolescence Health, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Lutz WalterPrimate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.
Markus UhrbergInstitute for Transplantation Diagnostics and Cell Therapeutics, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Heinrich Heine University Düsseldorf · DEGerman Primate Center · DETechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innate lymphoid cells (ILCs) and in particular ILC3s have been described to be vital for mucosal barrier functions and homeostasis within the gastrointestinal (GI) tract. Importantly, IL-22-secreting ILC3 have been implicated in the control of inflammatory bowel disease (IBD) and were shown to reduce the incidence of graft-versus-host disease (GvHD) as well as the risk of transplant rejection. Unfortunately, IL-22-secreting ILC3 are primarily located in mucosal tissues and are not found within the circulation, making access to them in humans challenging. On this account, there is a growing desire for clinically applicable protocols for

Indexed as

Hematopoietic Stem Cell TransplantationAntigens, CD34Cell Culture TechniquesCells, CulturedGastrointestinal TractHematopoiesisHumansImmunity, InnateInterleukin-17Interleukin-22InterleukinsLymphocytesLymphocyte TransfusionMesenchymal Stem CellsStem Cell NicheAntigens, CD34Interleukin-17Interleukin-22InterleukinsCD34 cells+GMP—Good Manufacturing Practicehematopoietic stem and progenitor cellsILC3innate lymphoid cells (ILCs)mesenchymal stem cellsumbilical cord stem cells (UCSC)

Identifiers

PMID35003122
PMCPMC8739490
OpenAlexW4200305074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.