Evidence map›Paper›PMID 35003118›Full record

ArticleFrontiers in immunology2021

Activin and BMP Signaling Activity Affects Different Aspects of Host Anti-Nematode Immunity in

Yaprak Ozakman, Dhaivat Raval, Ioannis Eleftherianos

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Genes · 2025
    Article
  2. Frontiers in microbiology · 2025
    Article
  3. The Activin Branch Ligand Daw Regulates theInternational journal of molecular sciences · 2024
    Article
  4. Functional role of the TGF-β signaling in theCurrent research in immunology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yaprak OzakmanInfection and Innate Immunity Laboratory, Department of Biological Sciences, The George Washington University, Washington, DC, United States.
Dhaivat RavalInfection and Innate Immunity Laboratory, Department of Biological Sciences, The George Washington University, Washington, DC, United States.
Ioannis EleftherianosInfection and Innate Immunity Laboratory, Department of Biological Sciences, The George Washington University, Washington, DC, United States.
George Washington University · US

Funding

Role of TGF-beta signaling in the Drosophila immune response against nematode-bacteria complexesR01AI110675 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI ELEFTHERIANOS, IOANNIS · 2015 to 2018
$954k
Role of TGF-Beta signaling in the Drosophila immune response against nematode-bacR56AI110675 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI ELEFTHERIANOS, IOANNIS · 2014 to 2014
$229k
NIAID NIH HHS R01 AI110675NIAID NIH HHS R56 AI110675
6 · The paper itself

Abstract

The multifaceted functions ranging from cellular and developmental mechanisms to inflammation and immunity have rendered TGF-ß signaling pathways as critical regulators of conserved biological processes. Recent studies have indicated that this evolutionary conserved signaling pathway among metazoans contributes to the

Indexed as

ActivinsAnimalsBone Morphogenetic ProteinsCecropinsDrosophila melanogasterDrosophila ProteinsDual OxidasesHost-Parasite InteractionsInsect ProteinsMutationReactive Oxygen SpeciesRhabditidaRhabditida InfectionsSignal TransductionTransforming Growth Factor betaActivinsBone Morphogenetic ProteinsCecropinsDptA protein, DrosophilaDrosophila ProteinsDual OxidasesInsect ProteinsReactive Oxygen SpeciesTransforming Growth Factor betaDrosophilaHeterorhabditisinnate immunityPhotorhabdusTGF-ß

Identifiers

PMID35003118
PMCPMC8727596
OpenAlexW4200380807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.