ArticleFrontiers in microbiology2021
Bacterial Signatures of Paediatric Respiratory Disease: An Individual Participant Data Meta-Analysis.
Registry-linked trialOpen access · goldAbstract read
In one paragraph
Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07232550 (Biomarkers and Respiratory Omics as New CHildren Opportunities - Study of Clinical Outcomes and Predictivity Evaluation - a Multi-cohort, Multi-center Study), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Biomarkers and Respiratory Omics as New CHildren Opportunities - Study of Clinical Outcomes and Predictivity Evaluation - a Multi-cohort, Multi-center Study
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Bronchiectasis in children: a systematic review of cytokine profile, immune cell phenotypes and microbiota in bronchoalveolar lavage fluid.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- Airway microbiota in young people across four continents differ by country, asthma status and inflammatory phenotype.Thorax · 2026Article
- Functional and Resistome Profiling of Paediatric Airway Microbiota in Asthma Using Shotgun Metagenomics.Biomedicines · 2026Article
- Exploring Bifidobacteria-Fermented Dairy Products: Innovations, Challenges, and Health-Related Insights.Current microbiology · 2026Review
- Reassessing viral origins and evolutionary placement in the tree of life.Antonie van Leeuwenhoek · 2026Review
- Benchmarking 16S rRNA Gene-Based Approaches to Bacterial Taxonomy Assignment Based on Amplicon Sequencing With Illumina and Oxford Nanopore.International journal of microbiology · 2025Article
- Dpr-mediated HJournal of bacteriology · 2024Article
- Time to re-set our thinking about airways disease: lessons from history, the resurgence of chronic bronchitis / PBB and modern concepts in microbiology.Frontiers in pediatrics · 2024Review
- The Respiratory Microbiome in Paediatric Chronic Wet Cough: What Is Known and Future Directions.Journal of clinical medicine · 2023Review
- Realising respiratory microbiomic meta-analyses: time for a standardised framework.Microbiome · 2023Article
- 16S rRNA gene-based microbiota profiles from diverse avian faeces are largely independent of DNA preservation and extraction method.Frontiers in microbiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
38 authors at 20 institutions in 12 countries.
David T J BroderickSchool of Biological Sciences, University of Auckland, Auckland, New Zealand.
David W WaiteSchool of Biological Sciences, University of Auckland, Auckland, New Zealand.
Robyn L MarshChild Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia.
Carlos A CamargoDepartment of Emergency Medicine, Massachusetts General Hospital, Boston, MA, United States.
Paul CardenasColegio de Ciencias Biológicas y Ambientales, Instituto de Microbiología, Universidad San Francisco de Quito, Quito, Ecuador.
Anne B ChangChild Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia.
William O C CooksonNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Leah CuthbertsonRoyal Brompton and Harefield NHS Foundation Trust, London, United Kingdom.
Wenkui DaiDepartment of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China.
Mark L EverardSchool of Medicine, University of Western Australia, Perth, WA, Australia.
Alain GervaixDepartment of Pediatrics, Gynecology and Obstetrics, Faculty of Medicine, University Hospitals of Geneva, Geneva, Switzerland.
J Kirk HarrisDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, CO, United States.
Kohei HasegawaDepartment of Emergency Medicine, Massachusetts General Hospital, Boston, MA, United States.
Lucas R HoffmanSeattle Children's Hospital, Seattle, WA, United States.
Soo-Jong HongDepartment of Pediatrics, Childhood Asthma Atopy Center, Humidifier Disinfectant Health Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Laurence JossetHospices Civils de Lyon, Lyon, France.
Matthew S KellyDivision of Pediatric Infectious Diseases, Duke University, Durham, NC, United States.
Bong-Soo KimDepartment of Life Science, Multidisciplinary Genome Institute, Hallym University, Chuncheon, South Korea.
Yong KongDepartment of Biostatistics, Yale School of Public Health, Yale University, New Haven, CT, United States.
Shuai C LiDepartment of Computer Science, City University of Hong Kong, Kowloon, Hong Kong SAR, China.
Jonathan M MansbachHarvard Medical School, Boston, MA, United States.
Asuncion MejiasDivision of Pediatric Infectious Diseases, Department of Pediatrics, Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, United States.
George A O'TooleDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, United States.
Laura PaalanenFinnish Institute for Health and Welfare (THL), Helsinki, Finland.
Marcos Pérez-LosadaDepartment of Biostatistics and Bioinformatics, Computational Biology Institute, Milken Institute School of Public Health, George Washington University, Washington, DC, United States.
Melinda M PettigrewDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, United States.
Maxime PichonCHU Poitiers, Infectious Agents Department, Poitiers, France.
Octavio RamiloDivision of Pediatric Infectious Diseases, Department of Pediatrics, Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, United States.
Lasse RuokolainenDepartment of Biosciences, University of Helsinki, Helsinki, Finland.
Olga SakwinskaNestlé Research, Lausanne, Switzerland.
Patrick C SeedDepartment of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Christopher J van der GastDepartment of Life Sciences, Manchester Metropolitan University, Manchester, United Kingdom.
Brandie D WagnerDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado, Aurora, Aurora, CO, United States.
Hana YiSchool of Biosystem and Biomedical Science, Korea University, Seoul, South Korea.
Edith T ZemanickDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, CO, United States.
Yuejie ZhengShenzhen Children's Hospital, Shenzhen, China.
Naveen PillarisettiStarship Children's Hospital, Auckland, New Zealand.
Michael W TaylorSchool of Biological Sciences, University of Auckland, Auckland, New Zealand.
University of Auckland · NZCharles Darwin University · AUHarvard University · USRoyal Brompton & Harefield NHS Foundation Trust · GBUniversity of Colorado Denver · USYale University · USAsan Medical Center · KRCity University of Hong Kong · HKDartmouth College · USDuke University · USFinnish Institute for Health and Welfare · FIHallym University · KRHospices Civils de Lyon · FRKorea University · KRManchester Metropolitan University · GBMassachusetts General Hospital · USNationwide Children's Hospital · USNestlé (Switzerland) · CHNorthwestern University · USPeking University Shenzhen Hospital · CN
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MNCATS NIH HHS UL1 TR001863
Abstract
PubMed holds no abstract for this paper.
Indexed as
individual participant data (IPD) meta-analysismeta-analysismicrobiota (16S)paediatricsrespiratory infectionrespiratory tract
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
NCT07232550ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.