Evidence map›Paper›PMID 35002981›Full record

ArticleFrontiers in endocrinology2021

Comparison of Muscle Density in Middle-Aged and Older Chinese Adults Between a High-Altitude Area (Kunming) and a Low-Altitude Area (Beijing).

Xingli Liu, Ling Wang, Meng Gao, Gang Wang, Kai Tang, Jin Yang, Wei Song, Jingsong Yang, Liang Lyu, Xiaoguang Cheng

Open access · goldAbstract readComparative Study
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Circulating immunometabolic signatures of sarcopenia at high altitude.The journal of nutrition, health & aging · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Xingli LiuFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Ling WangDepartment of Radiology, Beijing Jishuitan Hospital, Beijing, China.
Meng GaoDepartment of Radiology, The First People's Hospital of Yunnan Province, Kunming, China.
Gang WangDepartment of Radiology, The First People's Hospital of Yunnan Province, Kunming, China.
Kai TangMedical School, Kunming University of Science and Technology, Kunming, China.
Jin YangMedical School, Kunming University of Science and Technology, Kunming, China.
Wei SongFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Jingsong YangDepartment of Radiology, The First People's Hospital of Yunnan Province, Kunming, China.
Liang LyuFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Xiaoguang ChengDepartment of Radiology, Beijing Jishuitan Hospital, Beijing, China.
Kunming University of Science and Technology · CNFirst People's Hospital of Yunnan Province · CNBeijing Jishuitan Hospital · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Purpose: A high-altitude environment was known to have a negative effect on bone and lead to a higher incidence of hip fracture. However, the dependence of muscle composition on altitude is unclear. Thus, we aimed to compare muscle density and area in plateau and low altitude area and to determine the effect of the altitude on these outcomes. Methods: Community dwelling adults over 60 years old living in Beijing (elevation 50 m; 300 subjects,107 men and 193 women) or Kunming (elevation 2000 m; 218 subjects,83 men and 135 women) for more than 10 years were enrolled. Quantitative CT was performed in all subjects and cross-sectional area and attenuation measured in Hounsfield units (HU) were determined for the trunk, gluteus, and mid-thigh muscles. Results: Compared to Beijing, Kunming adults were slimmer (Beijing men Conclusions: Compared with Beijing, the adults in Kunming had higher muscle density of the gluteus maximus and L2 trunk muscles, showing that living at a higher altitude might be beneficial to muscle quality.

Indexed as

AltitudeAsian PeopleAgedBeijingCohort StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedMuscle, SkeletalTomography, X-Ray Computedaltitudecomputed tomographymuscle areamuscle densityolder adults

Identifiers

PMID35002981
PMCPMC8740240
OpenAlexW4200233119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.