Evidence map›Paper›PMID 35002630›Full record

ReviewFrontiers in cellular neuroscience2021

Astrocyte and Oligodendrocyte Responses From the Subventricular Zone After Injury.

Jennifer David-Bercholz, Chay T Kuo, Benjamin Deneen

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  9. Glioblastoma Therapy: Past, Present and Future.International journal of molecular sciences · 2024
    Review
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  16. Publicly availableFrontiers in neuroscience · 2023
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jennifer David-BercholzDepartment of Cell Biology, Duke University School of Medicine, Durham, NC, United States.
Chay T KuoDepartment of Cell Biology, Duke University School of Medicine, Durham, NC, United States.
Benjamin DeneenCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, United States.
Duke University · USBaylor College of Medicine · US

Funding

MOLECULAR AND CELLULAR CONTROL OF INJURY-INDUCED ASTROGENESISR01NS096096 · NINDS · DUKE UNIVERSITY · PI DENEEN, BENJAMIN · 2017 to 2021
$2.6M
NINDS NIH HHS R01 NS096096
6 · The paper itself

Abstract

Under normal conditions, neural stem cells (NSCs or B cells) in the adult subventricular zone (SVZ) give rise to amplifying neural progenitor cells (NPCs or C cells), which can produce neuroblasts (or A cells) that migrate to the olfactory bulb and differentiate into new neurons. However, following brain injury, these cells migrate toward the injury site where they differentiate into astrocytes and oligodendrocytes. In this review, we will focus on recent findings that chronicle how astrocytes and oligodendrocytes derived from SVZ-NSCs respond to different types of injury. We will also discuss molecular regulators of SVZ-NSC proliferation and their differentiation into astrocytes and oligodendrocytes. Overall, the goal of this review is to highlight how SVZ-NSCs respond to injury and to summarize the regulatory mechanisms that oversee their glial response. These molecular and cellular processes will provide critical insights needed to develop strategies to promote brain repair following injury using SVZ-NSCs.

Indexed as

astrocytesinjuryneural stem cellnicheoligodendrocytesSVZ

Identifiers

PMID35002630
PMCPMC8740317
OpenAlexW4200627169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.