Evidence map›Paper›PMID 35002529›Full record

ArticleInternational journal of biological sciences2022

CircCDK14 Promotes Tumor Progression and Resists Ferroptosis in Glioma by Regulating PDGFRA.

Simin Chen, Zhaoyu Zhang, Baoxin Zhang, Qing Huang, Yi Liu, Yi Qiu, Xinmiao Long, Minghua Wu, Zuping Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Simin ChenSchool of Basic Medical Science, Central South University, Changsha 410013, Hunan, China.
Zhaoyu ZhangSchool of Basic Medical Science, Central South University, Changsha 410013, Hunan, China.
Baoxin ZhangArmed Police Hospital of Hunan Province, Changsha 410013, Hunan, China.
Qing HuangSchool of Basic Medical Science, Central South University, Changsha 410013, Hunan, China.
Yi LiuDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410013, Hunan, China.
Yi QiuSchool of Basic Medical Science, Central South University, Changsha 410013, Hunan, China.
Xinmiao LongSchool of Basic Medical Science, Central South University, Changsha 410013, Hunan, China.
Minghua WuCancer Research Institute, Central South University, Changsha 410013, Hunan, China.
Zuping ZhangSchool of Basic Medical Science, Central South University, Changsha 410013, Hunan, China.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CircRNAs have garnered significant interest in recent years due to their regulation in human tumorigenesis, yet, the function of most glioma-related circRNAs remains unclear. In this study, using RNA-Seq, we screened differentially regulated circRNAs in glioma, in comparison to non-tumor brain tissue. Loss- and gain-of-function strategies were used to assess the effect of circCDK14 on tumor progression both

Indexed as

Gene Expression Regulation, NeoplasticAnimalsCarcinogenesisCell Line, TumorCell ProliferationCyclin-Dependent KinasesDisease ProgressionFemaleFerroptosisGliomaHumansIn Situ Hybridization, FluorescenceMiceMice, Inbred BALB CMice, NudeMicroRNAsCDK14 protein, humanCyclin-Dependent KinasesMicroRNAsPDGFRB protein, humanReceptor, Platelet-Derived Growth Factor betaRNA, CircularCircCDK14FerroptosisGliomamiR-3938PDGFRA

Identifiers

PMID35002529
PMCPMC8741855
OpenAlexW4206756645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.