Evidence map›Paper›PMID 35002517›Full record

ReviewInternational journal of biological sciences2022

Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells.

Swati Haldar, Himanshu Agrawal, Sarama Saha, Alex R Straughn, Partha Roy, Sham S Kakar

Open access · goldAbstract readReview
In one paragraph

Review in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Significance ofInternational journal of reproductive biomedicine · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Swati HaldarMolecular Endocrinology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Uttarakhand 247667, India.
Himanshu AgrawalMolecular Endocrinology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Uttarakhand 247667, India.
Sarama SahaDepartment of Biochemistry, All India Institute of Medical Sciences Rishikesh, Uttarakhand 249203, India.
Alex R StraughnDepartment of Physiology, James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA.
Partha RoyMolecular Endocrinology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Uttarakhand 247667, India.
Sham S KakarDepartment of Physiology, James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA.
Indian Institute of Technology Roorkee · IN

Funding

Current Trends in Stem Cell TherapiesT32HL134644 · NHLBI · UNIVERSITY OF LOUISVILLE · PI KAKAR, SHAM S., RATAJCZAK, MARIUSZ Z · 2017 to 2021
$1.4M
UofL Bridges to Baccalaureate(ULBB)R25GM133328 · NIGMS · UNIVERSITY OF LOUISVILLE · PI DAVIS, RANDALL, KAKAR, SHAM S. · 2019 to 2023
$732k
NHLBI NIH HHS T32 HL134644NIGMS NIH HHS R25 GM133328
6 · The paper itself

Abstract

Follicle stimulating hormone (FSH) and its receptor (FSHR) have been reported to be responsible for several physiological functions and cancers. The responsiveness of stem cells and cancer stem cells towards the FSH-FSHR system make the function of FSH and its receptors more interesting in the context of cancer biology. This review is comprised of comprehensive information on FSH-FSHR signaling in normal physiology, gonadal stem cells, cancer cells, and potential options of utilizing FSH-FSHR system as an anti-cancer therapeutic target.

Indexed as

AnimalsFollicle Stimulating HormoneHumansNeoplasmsNeoplastic Stem CellsReceptors, FSHReproductionSignal TransductionFollicle Stimulating HormoneReceptors, FSH

Identifiers

PMID35002517
PMCPMC8741861
OpenAlexW4200437746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.