Evidence map›Paper›PMID 35002398›Full record

ArticleSaudi journal of biological sciences2022

Mutational analysis of

Ashok Kumar Narsani, Ali Muhammad Waryah, Muhammad Rafiq, Hina Shaikh, Syed Habib Ahmed Naqvi, Raveet Kumar, Pawan Kumar

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Analysis ofInternational journal of ophthalmology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ashok Kumar NarsaniInstitute of Biotechnology & Genetic Engineering, University of Sindh, Jamshoro, Pakistan.
Ali Muhammad WaryahDepartment Molecular Biology and Genetics, Medical Research Center, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Muhammad RafiqInstitute of Biotechnology & Genetic Engineering, University of Sindh, Jamshoro, Pakistan.
Hina ShaikhDepartment Molecular Biology and Genetics, Medical Research Center, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Syed Habib Ahmed NaqviInstitute of Biotechnology & Genetic Engineering, University of Sindh, Jamshoro, Pakistan.
Raveet KumarDepartment of Ophthalmology, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Pawan KumarDepartment of Ophthalmology, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Liaquat University of Medical & Health Sciences · PKUniversity of Sindh · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary open angle glaucoma (POAG) occurs due to the discrepancies in the angle of anterior chamber characterized by the alterations in intraocular pressure, optic nerves head changes and central loss of visual field. In molecular research,

methodsAfter consent, total n = 88 POAG patients undergone through standard ophthalmological investigations before their recruitment in this study. The blood samples were utilized for DNA isolation. The genotyping of

resultsIt was evident that the frequencies of heterozygous G/A and homozygous mutants A/A genotypes were higher in males (36.5%, 7.7%) than females (30.6%, 2.8%) of POAG population. Furthermore, the juvenile patients exhibit high manifestation of carrier genotype (66.6%) in comparison to adult patients (31.7%). The results also indicated the significant relationship of intraocular pressure with homozygous mutant A/A genotype of

conclusionsOur study provided the mutational data of

Indexed as

CYP1B1 variantMutationPrimary open angle glaucomaSanger sequencing

Identifiers

PMID35002398
PMCPMC8716894
OpenAlexW3195708470

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.