Evidence map›Paper›PMID 35002350›Full record

ReviewClinical Medicine Insights. Cardiology2022

Takotsubo Syndrome: A Review of Presentation, Diagnosis and Management.

Joseph Assad, Giuseppe Femia, Patrick Pender, Tamer Badie, Rohan Rajaratnam

Open access · goldAbstract readReview
In one paragraph

Review in Clinical Medicine Insights. Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 2 pooled it
18.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 2 syntheses or guidelines pooled it, 124 citations in OpenAlex.

  1. Pooled it
  2. Brazilian Guideline on Menopausal Cardiovascular Health - 2024.Arquivos brasileiros de cardiologia · 2024
    Guideline
  3. A novel parameter for risk stratification in patients with takotsubo syndrome.American heart journal plus : cardiology research and practice · 2026
    Article
  4. Review
  5. Article
  6. Incidence of ischemic stroke in Takotsubo cardiomyopathy patients: a systematic review and meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Women's cardiovascular health in 2025:Saudi medical journal · 2026
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. [Rare cases of stress cardiomyopathy triggered by pulmonary embolism and reverse Takotsubo].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Article
  18. Article
  19. Review
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joseph AssadDepartment of Cardiology, Liverpool Hospital, Liverpool, NSW, Australia.ORCID https://orcid.org/0000-0001-9234-3104
Giuseppe FemiaDepartment of Cardiology, Liverpool Hospital, Liverpool, NSW, Australia.ORCID https://orcid.org/0000-0002-7144-7040
Patrick PenderDepartment of Cardiology, Liverpool Hospital, Liverpool, NSW, Australia.
Tamer BadieDepartment of Cardiology, Liverpool Hospital, Liverpool, NSW, Australia.
Rohan RajaratnamDepartment of Cardiology, Liverpool Hospital, Liverpool, NSW, Australia.
Camden and Campbelltown Hospitals · AULiverpool Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Takotsubo Syndrome (TTS) is a condition of transient left ventricular dysfunction that is typically triggered by emotional or physical stress. Since first described in Japan in 1990, it has increasingly been recognised in clinical practice, accounting for up to 2% of Acute Coronary Syndrome (ACS) presentations. In fact, the clinical presentation can be indistinguishable from a myocardial infarction. Although current evidence suggests a catecholamine induced myocardial stunning, the pathophysiological mechanisms remain unknown. Interestingly, it is more common in woman, particularly those who are post-menopausal. This review aims to summarise the current research and provide an overview of the diagnostic strategies and treatment options.

Indexed as

broken heart syndromestress cardiomyopathyTakotsubo cardiomyopathyTakotsubo syndrome

Identifiers

PMID35002350
PMCPMC8733363
OpenAlexW4205332053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.