ArticleNature and science of sleep2021
Fragmented Sleep and the Prevalence of Hypertension in Middle-Aged and Older Individuals.
Article in Nature and science of sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- The Link Between Sleep Health Dimensions and Hypertension for Cardiovascular Health.Current epidemiology reports · 2026Review
- The association between sleep fragmentation and incident atrial fibrillation: a prospective cohort study in a community population.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Sleep timing and the prevalence of hypertension in middle-aged and older populations: the sleep heart health study.BMC psychiatry · 2024Article
- Association of sleep timing with all-cause and cardiovascular mortality: the Sleep Heart Health Study and the Osteoporotic Fractures in Men Study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Objective sleep characteristics and hypertension: a community-based cohort study.Frontiers in cardiovascular medicine · 2024Article
- Association Between Sleep Efficiency and Hypertension in Chinese Obstructive Sleep Apnea Patients.Nature and science of sleep · 2023Article
- Effect of Sleep Duration on Blood Pressure in Patients with SARS-CoV-2 Infection and Hypertensive Urgencies in Shanghai Fangcang Shelter Hospital.Infection and drug resistance · 2023Article
- Polysomnographic Evaluation of Sleep Bruxism Intensity and Sleep Architecture in Nonapneic Hypertensives: A Prospective, Observational Study.Journal of clinical medicine · 2022Article
- Sleep Efficiency May Predict Depression in a Large Population-Based Study.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveWe aimed to investigate the association between fragmented sleep and the prevalence of hypertension in middle-aged and older individuals.
methodsThis study included 5804 participants with an average age of 63.1±11.2 years from the Sleep Heart Health Study. Fragmented sleep parameters including arousal index in total sleep (ArI-Total), rapid eye movement sleep (ArI-REM), non-rapid eye movement sleep (ArI-NREM), fragmented sleep index (SFI), sleep efficiency (SE) and wake after sleep onset (WASO) were monitored using polysomnography. The information on hypertension, defined as systolic blood pressure (SBP) ≥140 mmHg and/or diastolic blood pressure (DBP) ≥90 mmHg or under antihypertensive treatment, was collected at baseline. We conducted multivariable logistic regression to explore the cross-sectional association between fragmented sleep and the prevalence of hypertension.
resultsAfter adjusting for potential confounders, fragmented sleep parameters (per 5-unit change) including SE (odds ratio [OR] 0.904; 95% confidence interval [CI] 0.877-0.932; P < 0.001), WASO (OR 1.019; 95% CI 1.012-1.027; P < 0.001), ArI-Total (OR, 1.036; 95% CI, 1.005-1.068; P = 0.024), and ArI-NREM (OR 1.032; 95% CI 1.004-1.062; P = 0.027) were significantly associated with the prevalence of hypertension. In addition, ArI-Total, ArI-NREM, and ArI-REM were positively correlated with both systolic blood pressure and diastolic blood pressure.
conclusionWe found a high prevalence of hypertension among middle-aged and older individuals with fragmented sleep. The causal association between fragmented sleep and hypertension warrants further investigation.
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