ArticleInternational journal of chronic obstructive pulmonary disease
Eosinopenia Predicting Long-term Mortality in Hospitalized Acute Exacerbation of COPD Patients with Community-acquired Pneumonia-A Retrospective Analysis.
Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Predictive value of neutrophil-lymphocyte ratio for all-cause mortality in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis.BMC pulmonary medicine · 2025Pooled it
- Observational
- Association of eosinophil levels with 30-day overall mortality in hospitalized patients with aspiration pneumonia.Scientific reports · 2026Article
- Eosinopenia and prognosis in severe community-acquired pneumonia.Pneumonia (Nathan Qld.) · 2026Article
- Unraveling immune-inflammation-aging network interactions: an interpretable machine learning model predicts the risk of postherpetic neuralgia.Frontiers in immunology · 2026Article
- Exploring the correlation between eosinophils with clinical risk of severe pneumonia based on MIMIC-IV data.Scientific reports · 2025Article
- Nonlinear association between blood eosinophil counts and clinical outcomes in ICU-Admitted patients with acute exacerbation of COPD: a retrospective observational study.BMC pulmonary medicine · 2025Observational
- Article
- Article
- Article
- Eosinophilia Is a Favorable Marker for Pneumonia in Chronic Obstructive Pulmonary Disease.Tuberculosis and respiratory diseases · 2024Article
- Eosinophil count and clinical outcome in patients with acute exacerbation of Chronic obstructive pulmonary disease.Journal of preventive medicine and hygiene · 2024Article
- Comprehensive Nomograms Using Routine Biomarkers Beyond Eosinophil Levels: Enhancing Predictability of Corticosteroid Treatment Outcomes in AECOPD.Journal of inflammation research · 2024Article
- Development of a nomogram to estimate the risk of community-acquired pneumonia in adults with acute asthma exacerbations.The clinical respiratory journal · 2023Article
- Blood Eosinophils and Clinical Outcomes in Inpatients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Prospective Cohort Study.International journal of chronic obstructive pulmonary disease · 2023Article
- Decreased capsaicin cough reflex sensitivity predicts hospitalisation due to COPD.BMJ open respiratory research · 2023Article
- Evaluation of Eosinopenia as a SIRS Biomarker in Critically Ill Horses.Animals : an open access journal from MDPI · 2022Article
- The Saudi Thoracic Society evidence-based guidelines for the diagnosis and management of community-acquired pneumonia in children and adults.Annals of thoracic medicineArticle
- Predicting 30-day readmissions in pneumonia patients using machine learning and residential greenness.Digital healthArticle
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute exacerbation of chronic obstructive pulmonary disease (AECOPD) could be triggered by community-acquired pneumonia (CAP). Peripheral blood eosinopenia are strongly associated with increased mortality. In hospitalized AECOPD patients with CAP, eosinopenia may be used to identify patients with high risk of death on admission.
methodsWe conducted a retrospective cohort study in 82 hospitalized AECOPD patients with CAP. Patients who had received systemic corticosteroids preadmission were excluded. The patients were identified by individual case file review. According to blood eosinophil count, patients were grouped as eosinopenia (<50/μL) and non-eosinopenia (≥50/μL). Association of eosinopenia with infection and 18-month survival were analyzed using appropriate statistical methods.
resultsBaseline demographic, comorbidity, CURB65 and Pneumonia Severity Index scores were similar between two groups. The eosinopenia group had significantly higher pro-brain natriuretic peptide, D-dimer, neutrophil percentage, and lower lymphocyte count and lymphocyte percentage. The eosinopenia group had significantly higher C-reactive protein (median 77.30 vs 16.55,
conclusionEosinopenia (<50/μL) was a strong predictor of 18-month mortality and associated with more severe infection in hospitalized AECOPD patients with CAP. Eosinophil count at admission can be used as a prognosis marker of mortality in those population.
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