Evidence map›Paper›PMID 35002178›Full record

ReviewJournal of Ayurveda and integrative medicine

AYUSH- 64: A potential therapeutic agent in COVID-19.

Ashok Kumar Panda, Sarbeswar Kar, Amit Kumar Rai, B C S Rao, N Srikanth

Open access · goldAbstract readReview
In one paragraph

Review in Journal of Ayurveda and integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ashok Kumar PandaCentral Ayurveda Research Institute, Bhubaneswar, Odisha, Central Council of Research in Ayurveda Sciences, Ministry of AYUSH, Govt. of India, India. Electronic address: akpanda_06@yahoo.co.in.
Sarbeswar KarJSS Ayurveda Medical College &Hospital, Mysore, Karnataka, India.
Amit Kumar RaiCentral Council of Research in Ayurveda Sciences, Ministry of AYUSH, Govt. of India, India.
B C S RaoCentral Council of Research in Ayurveda Sciences, Ministry of AYUSH, Govt. of India, India.
N SrikanthCentral Council of Research in Ayurveda Sciences, Ministry of AYUSH, Govt. of India, India.
Central Council for Research in Ayurvedic Science · INJSS Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corona Virus disease (COVID-19) has become a global pandemic resulting in large scale morbidity and mortality worldwide. The management of COVID-19 has been a big challenge because of multifactorial pathophysiology and no specific treatment. AYUSH-64, a poly-herbal formulation developed by CCRAS, Ministry of AYUSH, Govt. of India through extensive pharmacological, toxicological and clinical studies has proven its safety and efficacy in infective febrile conditions such as malaria and influenza. AYUSH- 64 has four ingredients having immunomodulatory, anti-inflammatory, antipyretic, antioxidant and anti-viral activities. It arrests the extreme inflammatory responses in COVID-19 that causes progression to significant morbidity. AYUSH-64 has also been incorporated in the National COVID management protocol based on Ayurveda and Yoga by Government of India for asymptomatic and mild cases of COVID-19. Further, on the basis of tangible evidence generated through robust clinical and experimental studies on AYUSH-64, the Ministry of AYUSH has launched nation-wide campaign for mass distribution of AYUSH-64 to asymptomatic, mild to moderate COVID-19 patients in home isolation to reduce the burden on the hospital. This review will highlight the specifications of AYUSH-64, its mechanism of action, its repurposing for COVID-19, various clinical and experimental studies.

Indexed as

AyurvedaAYUSH-64Corona virus diseaseCOVID-19ImmunomodulationSARS-CoV-2

Identifiers

PMID35002178
PMCPMC8723836
OpenAlexW4205551041

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.