Evidence map›Paper›PMID 35001949›Full record

ArticleIndian journal of anaesthesia2021

Comparison of effects of dexmedetomidine added to ropivacaine versus ropivacaine alone infiltration scalp block for attenuation of the haemodynamic response to skull pin placement in neurosurgical procedures: A double-blind, randomised clinical trial.

B N Sahana, Sri Devi Radhapuram, Aloka Samantaray, Natham Hemanth, Hemalatha Pasupuleti, Hanumantha Rao Mangu

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of anaesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Dexmedetomidine: A drug for all seasons?Indian journal of anaesthesia · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

B N SahanaDepartment of Anaesthesiology and Critical care, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
Sri Devi RadhapuramDepartment of Anaesthesiology and Critical care, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
Aloka SamantarayDepartment of Anaesthesiology and Critical care, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
Natham HemanthDepartment of Anaesthesiology and Critical care, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
Hemalatha PasupuletiDepartment of Anaesthesiology and Critical care, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
Hanumantha Rao ManguDepartment of Anaesthesiology and Critical care, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
Sri Venkateswara Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsSkull pin head holder application is intensely painful and is accompanied with abrupt increase in heart rate and arterial blood pressure. We aimed to determine the effects of adding dexmedetomidine to ropivacaine scalp block in attenuating the haemodynamic response to skull pin insertion in neurosurgical procedures.

methodsSixty patients were randomly allocated to receive scalp block with 25 ml of 0.5% ropivacaine added with either normal saline (control group) or dexmedetomidine (1 μg/kg) after anesthesia induction. A standard uniform general endotracheal anaesthesia protocol was followed in all study subjects. Heart rate and blood pressure measurements were made at baseline, 1, 3, 5, 10, and 15 min following skull pin placement. Student's independent

resultsThere was no significant attenuation of heart rate (

conclusionsThe addition of dexmedetomidine (1 μg/kg) to 25 ml of 0.5% ropivacaine offers no additional benefit over 25 ml of 0.5% ropivacaine alone scalp block in attenuating the haemodynamic response to skull pin placement in neurosurgical procedures.

Indexed as

Blood pressuredexmedetomidineheart ratenerve blockropivacaine

Identifiers

PMID35001949
PMCPMC8680418
OpenAlexW4206271994

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.