Evidence map›Paper›PMID 35001703›Full record

SynthesisInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2023

Acute isolated posterior cerebral artery stroke treated with mechanical thrombectomy: A single-center experience and review of the literature.

Ammad A Baig, Andre Monteiro, Muhammad Waqas, Justin M Cappuzzo, Manhal Siddiqi, Jacob Doane, Rimal H Dossani, Faisal Almayman, Wasiq I Khawar, Jason M Davies and 3 more

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 4 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Perfusion imaging parameters predict long-term clinical outcome in isolated posterior cerebral artery occlusion stroke patients.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Ammad A BaigDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, 12291University at Buffalo, Buffalo, NY, USA.
Andre MonteiroDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, 12291University at Buffalo, Buffalo, NY, USA.
Muhammad WaqasDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, 12291University at Buffalo, Buffalo, NY, USA.ORCID 0000-0003-4500-7954
Justin M CappuzzoDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, 12291University at Buffalo, Buffalo, NY, USA.
Manhal SiddiqiDepartment of Neurosurgery, 23564Gates Vascular Institute at Kaleida Health, Buffalo, NY, USA.
Jacob DoaneDepartment of Neurosurgery, 23564Gates Vascular Institute at Kaleida Health, Buffalo, NY, USA.
Rimal H DossaniDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, 12291University at Buffalo, Buffalo, NY, USA.
Faisal AlmaymanDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, 12291University at Buffalo, Buffalo, NY, USA.
Wasiq I KhawarDepartment of Neurosurgery, 23564Gates Vascular Institute at Kaleida Health, Buffalo, NY, USA.ORCID 0000-0001-7966-6005
Jason M DaviesDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, 12291University at Buffalo, Buffalo, NY, USA.ORCID 0000-0002-5225-3072
Kenneth V SnyderDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, 12291University at Buffalo, Buffalo, NY, USA.
Elad I LevyDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, 12291University at Buffalo, Buffalo, NY, USA.ORCID 0000-0002-6208-3724
Adnan H SiddiquiDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, 12291University at Buffalo, Buffalo, NY, USA.ORCID 0000-0002-9519-0059
Kaleida Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute isolated posterior cerebral artery (PCA) occlusions account for 5-10% of all ischemic events. Due to peculiar patient presentation, the potential benefit of mechanical thrombectomy (MT) remains controversial. We evaluated the safety, feasibility, and effectiveness of MT in our patients and compared our results with the literature review conducted.

methodsCharts were reviewed retrospectively for consecutive patients diagnosed with acute PCA stroke who underwent MT. Demographics, procedural, and follow-up details were noted. For the literature review, a systematic search of PubMed, MEDLINE, and EMBASE databases was conducted for the keywords "posterior cerebral artery" and "thrombectomy" for articles published between January 1, 2010 and June 30, 2021. Estimated rates for recanalization, favorable outcomes (modified Rankin Scale [mRS] score 0-2), symptomatic intracerebral hemorrhage (sICH), and mortality were extracted.

resultsOur cohort included 21 patients. Mean age was 71.2 years (standard deviation [SD] ± 10.2). Median National Institutes of Health Stroke Scale (NIHSS) presentation score was 9 (interquartile range [IQR] 5-15), with visual symptoms reported in 12(57.1%) patients. Overall, final modified thrombolysis in cerebral infarction (mTICI) 2b-3 was achieved in 17 patients (80.9%) with first-pass mTICI 2b-3 attained in 8 (38.1%). Postprocedure sICH occurred in 1 (4.8%) patient. Fifteen (71.4%) patients had a 0-2 mRS score at 90 days. Visual symptoms resolved in 10 of 12(83.3%) patients. Mortality occurred in 2 (9.5%) patients. For the systematic review, cohorts from 4 articles plus ours were included, totaling 222 patients. The estimated rate of successful recanalization was 85.25% (95% confidence interval[CI], 73.05%-97.45%), sICH was 3.60% (95% CI, 1.11%-6.09%), and mortality was 10.51% (95% CI, 5.88%-15.15%).

conclusionThe results of our series and systematic review indicate MT as a potentially safe and effective treatment modality for acute PCA stroke. These results also indicate that patient selection and assessment may be the key in obtaining favorable outcomes.

Indexed as

Brain IschemiaInfarction, Posterior Cerebral ArteryStrokeAgedCerebral InfarctionHumansRetrospective StudiesThrombectomyTreatment Outcomemechanical thrombectomyPosterior cerebral artery occlusionstroke

Identifiers

PMID35001703
PMCPMC9893240
OpenAlexW4206403282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.