Evidence map›Paper›PMID 35001688›Full record

ArticleEuropean journal of ophthalmology2022

Long-term outcomes in Primary congenital glaucoma, aniridia and anterior segment dysgenesis.

Tejal Magan, Alexander Tanner, Julia Fajardo-Sanchez, Kin Sheng Lim, Saurabh Goyal, Ian Rodrigues, Luis Amaya, Sameer Trikha, Avinash Kulkarni, Christopher Hammond and 2 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Ahmed Glaucoma Valve in Aniridia.Clinical ophthalmology (Auckland, N.Z.) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Tejal MaganFaculty of Life Sciences & Medicine, 111990King's College London, London, UK.
Alexander TannerFaculty of Life Sciences & Medicine, 111990King's College London, London, UK.
Julia Fajardo-SanchezFaculty of Life Sciences & Medicine, 111990King's College London, London, UK.
Kin Sheng LimFaculty of Life Sciences & Medicine, 111990King's College London, London, UK.
Saurabh GoyalDepartment of Ophthalmology, 111988St Thomas' Hospital, London, UK.
Ian RodriguesDepartment of Ophthalmology, 111988St Thomas' Hospital, London, UK.
Luis AmayaDepartment of Ophthalmology, 111988St Thomas' Hospital, London, UK.
Sameer TrikhaDepartment of Ophthalmology, 111990King's College Hospital, London, UK.
Avinash KulkarniDepartment of Ophthalmology, 111990King's College Hospital, London, UK.
Christopher HammondFaculty of Life Sciences & Medicine, 111990King's College London, London, UK.
Gerassimos LascaratosFaculty of Life Sciences & Medicine, 111990King's College London, London, UK.
Cynthia Yu-Wai-ManFaculty of Life Sciences & Medicine, 111990King's College London, London, UK.ORCID https://orcid.org/0000-0003-4868-5187
St Thomas' Hospital · GBKing's College Hospital · GBKing's College London · GB

Funding

Medical Research Council MR/T027932/1
6 · The paper itself

Abstract

aimTo determine the long-term outcomes of a cohort of complex patients with primary congenital glaucoma, aniridia and anterior segment dysgenesis.

methodsRetrospective consecutive series between 1990-2021 in two UK tertiary centres: Guy's and St Thomas' NHS Foundation Trust and King's College Hospital NHS Foundation Trust. We recorded the number and types of surgical and laser treatments along with preoperative and postoperative data, including intraocular pressures (IOP) and anti-glaucoma medications.

resultsA total of 41 eyes of 21 patients were included. Primary diagnoses were primary congenital glaucoma in 16 eyes (39.0%), aniridia in 14 eyes (34.2%), and anterior segment dysgenesis in 8 eyes (19.5%). Sixteen eyes (39.0%) had one or more glaucoma surgery or laser procedures for advanced glaucoma, and the long-term follow-up was 12.8 ± 3.6 years. There was a significant decrease in postoperative IOP (mmHg) at 3 months (16.5 ± 1.6;

conclusionsSurgical management of these complex eyes with advanced glaucoma is challenging. Overall, the cohort had good surgical outcomes with a significant decrease in IOP by 36.1% after long-term follow-up.

Indexed as

AniridiaGlaucomaTrabeculectomyEye AbnormalitiesFollow-Up StudiesHumansIntraocular PressureRetrospective StudiesTreatment OutcomeVisual Acuityaniridiaanterior segment dysgenesisglaucoma surgeryPrimary congenital glaucoma

Identifiers

PMID35001688
PMCPMC9373187
OpenAlexW4206749885

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.