Evidence map›Paper›PMID 35001682›Full record

ArticleEuropean journal of ophthalmology2022

Normative data on the foveal avascular zone in a young healthy Irish population using optical coherence tomography angiography.

Susan M O'Shea, Veronica M O'Dwyer, Grainne Scanlon

Abstract read
In one paragraph

Article in European journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. [Quantitative Assessment of Microvascular Changes in Diabetic Retinopathy and Their Association With Blood-Retinal Barrier Impairment].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Susan M O'SheaSchool of Physics, Clinical & Optometric Sciences. Technological University Dublin, Dublin, Ireland.ORCID https://orcid.org/0000-0002-2965-9699
Veronica M O'DwyerSchool of Physics, Clinical & Optometric Sciences. Technological University Dublin, Dublin, Ireland.
Grainne ScanlonSchool of Physics, Clinical & Optometric Sciences. Technological University Dublin, Dublin, Ireland.ORCID https://orcid.org/0000-0001-6956-5980

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo establish normative data on the size, shape and vascular profile of the foveal avascular zone (FAZ) in a young, healthy, Irish population, using the Cirrus 5000 HD-OCT. Certain diseases may alter FAZ appearance. Normative databases provide normal baseline values for comparison, thus improving diagnostic ability.

methodsOne hundred and fifty-four subjects aged 18-35 years old were recruited. Superficial FAZ area, diameter, circularity, ganglion cell layer, central macular thickness (CMT), vascular perfusion and density were measured using the Cirrus 5000. Axial length was measured with the IOL Master and blood pressure was measured using the Omron sphygmomanometer.

resultsMean FAZ area was 0.22 ± 0.07 mm

conclusionsThis study provides normative data for FAZ appearance and vascularity for the first time in a young, healthy, Irish population, using the Cirrus 5000 HD-OCT. Establishing machine and population specific normative data, particularly in relation to vessel density and perfusion is paramount to the early identification of ocular disease using Optical Coherence Tomography Angiography.

Indexed as

Macula LuteaTomography, Optical CoherenceAdolescentAdultFemaleFluorescein AngiographyFovea CentralisHumansMaleRetinal VesselsYoung Adultage-related macular degeneration < RETINAdiabetic retinopathy < RETINADiagnostic techniques < GLAUCOMAneuro maging < NEURO OPHTHALMOLOGYoptics/refraction/instruments < OPTICS / REFRACTION / NSTRUMENTStechniques of retinal examination < RETINA

Identifiers

PMID35001682
PMCPMC9373196

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.