Evidence map›Paper›PMID 35001681›Full record

ArticleJournal of dental research2022

Triacrylamide-Based Adhesives Stabilize Bonds in Physiologic Conditions.

F S de Lucena, S H Lewis, A P P Fugolin, A Y Furuse, J L Ferracane, C S Pfeifer

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Enhancing dentin bonding with catechol-based monomers by tailoring photoinitiator systems to overcome radical inhibition.Dental materials : official publication of the Academy of Dental Materials · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Current approaches to produce durable biomaterials: Trends in polymeric materials for restorative dentistry applications.Dental materials : official publication of the Academy of Dental Materials · 2024
    Review
  7. Article
  8. Article
  9. Multi-acrylamides improve bond stability through collagen reinforcement under physiological conditions.Dental materials : official publication of the Academy of Dental Materials · 2024
    Article
  10. Compatibility versus reaction diffusion: Factors that determine the heterogeneity of polymerized adhesive networks.Dental materials : official publication of the Academy of Dental Materials · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

F S de LucenaDepartment of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
S H LewisDivision of Biomaterials and Biomechanics, Department of Restorative Dentistry, School of Dentistry, Oregon Health & Science University, Portland, OR, USA.
A P P FugolinDivision of Biomaterials and Biomechanics, Department of Restorative Dentistry, School of Dentistry, Oregon Health & Science University, Portland, OR, USA.
A Y FuruseDepartment of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
J L FerracaneDivision of Biomaterials and Biomechanics, Department of Restorative Dentistry, School of Dentistry, Oregon Health & Science University, Portland, OR, USA.
C S PfeiferDivision of Biomaterials and Biomechanics, Department of Restorative Dentistry, School of Dentistry, Oregon Health & Science University, Portland, OR, USA.ORCID 0000-0002-1587-3838
Oregon Health & Science University · USUniversidade de São Paulo · BR

Funding

Novel polymeric materials with improved durability in the oral environment: tailoring responses to host and bacterial enzymes with anti-proteolytic and ecology-based antimicrobial approaches.R35DE029083 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI Carmem S. Pfeifer · 2019 to 2026
$8.1M
Tertiary methacrylamides and thiourethane additives as novel dental compositesU01DE023756 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI FERRACANE, JACK L., PFEIFER, CARMEM S. · 2013 to 2017
$2.4M
Smart Self-Sterilizing Dental Composites for Class V RestorationsR01DE026113 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI FERRACANE, JACK L., MERRITT, JUSTIN · 2016 to 2018
$1.2M
Novel dental composites based on methacrylamides and thiourethane oligomersK02DE025280 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI PFEIFER, CARMEM S. · 2016 to 2020
$600k
Host and bacterial enzyme-mediated approaches to produce durable direct and indirect restorationsR01DE028757 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI PFEIFER, CARMEM S. · 2019 to 2019
$495k
NIDCR NIH HHS K02 DE025280NIDCR NIH HHS R01 DE026113NIDCR NIH HHS R01 DE028757NIDCR NIH HHS R35 DE029083NIDCR NIH HHS U01 DE023756
6 · The paper itself

Abstract

In this study, an acrylamide-based adhesive was combined with a thiourethane-based composite to improve bond stability and reduce polymerization stress, respectively, of simulated composite restorations. The stability testing was conducted under physiologic conditions, combining mechanical and bacterial challenges. Urethane dimethacrylate was combined with a newly synthesized triacrylamide (TMAAEA) or HEMA (2-hydroxyethyl-methacrylate; control) to produce a 2-step total-etch adhesive system. Methacrylate-based composites (70 wt% silanized filler) were formulated, containing thiourethane oligomers at 0 (control) or 20 wt%. Standardized preparations in human third molars were restored; then, epoxy replicas were obtained from the occlusal surfaces before and after 7-d storage in water or with

Indexed as

Dental BondingDentin-Bonding AgentsAcrylamidesComposite ResinsDental CementsDentinHumansMaterials TestingMethacrylatesResin CementsTensile StrengthWaterAcrylamidesComposite ResinsDental CementsDentin-Bonding AgentsMethacrylatesResin CementsWateracrylamidesbiofilmdental adhesivesdental restoration failuresmechanical testingtooth demineralization

Identifiers

PMID35001681
PMCPMC9124905
OpenAlexW4205298170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.