Evidence map›Paper›PMID 35001658›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2022

Extracellular flux analyses reveal differences in mitochondrial PBMC metabolism between high-fit and low-fit females.

Joëlle J E Janssen, Bart Lagerwaard, Mojtaba Porbahaie, Arie G Nieuwenhuizen, Huub F J Savelkoul, R J Joost van Neerven, Jaap Keijer, Vincent C J de Boer

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Joëlle J E JanssenHuman and Animal Physiology, Wageningen University and Research, Wageningen, The Netherlands.ORCID 0000-0001-5709-8895
Bart LagerwaardHuman and Animal Physiology, Wageningen University and Research, Wageningen, The Netherlands.ORCID 0000-0001-8558-2385
Mojtaba PorbahaieCell Biology and Immunology, Wageningen University and Research, Wageningen, The Netherlands.ORCID 0000-0001-6446-9148
Arie G NieuwenhuizenHuman and Animal Physiology, Wageningen University and Research, Wageningen, The Netherlands.
Huub F J SavelkoulCell Biology and Immunology, Wageningen University and Research, Wageningen, The Netherlands.
R J Joost van NeervenCell Biology and Immunology, Wageningen University and Research, Wageningen, The Netherlands.ORCID 0000-0002-3991-5297
Jaap KeijerHuman and Animal Physiology, Wageningen University and Research, Wageningen, The Netherlands.ORCID 0000-0002-9720-7491
Vincent C J de BoerHuman and Animal Physiology, Wageningen University and Research, Wageningen, The Netherlands.ORCID 0000-0001-9928-1698
Wageningen University & Research · NLTiFN · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Analyzing metabolism of peripheral blood mononuclear cells (PBMCs) can possibly serve as a cellular metabolic read-out for lifestyle factors and lifestyle interventions. However, the impact of PBMC composition on PBMC metabolism is not yet clear, neither is the differential impact of a longer-term lifestyle factor versus a short-term lifestyle intervention. We investigated the effect of aerobic fitness level and a recent exercise bout on PBMC metabolism in females. PBMCs from 31 young female adults divided into a high-fit (V̇o

Indexed as

ProtonsAdolescentAdultExerciseExtracellular SpaceFemaleFlow CytometryGlycolysisHumansLeukocytes, MononuclearLife StyleMitochondriaOxygen ConsumptionPhysical EnduranceYoung AdultProtonsaerobic fitness levelbiomarkerlifestyleoxygen consumption ratePBMC metabolism

Identifiers

PMID35001658
PMCPMC8897018
OpenAlexW4205526730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.