Evidence map›Paper›PMID 35001649›Full record

ArticleJournal of the American Heart Association2022

Tobacco Consumption and High-Sensitivity Cardiac Troponin I in the General Population: The HUNT Study.

Julia Brox Skranes, Magnus Nakrem Lyngbakken, Kristian Hveem, Helge Røsjø, Torbjørn Omland

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Julia Brox SkranesDepartment of Cardiology Division of Medicine Akershus University Hospital Lørenskog Norway.ORCID 0000-0002-7139-5252
Magnus Nakrem LyngbakkenDepartment of Cardiology Division of Medicine Akershus University Hospital Lørenskog Norway.ORCID 0000-0002-5994-9304
Kristian HveemInstitute of Clinical MedicineUniversity of Oslo Oslo Norway.
Helge RøsjøDivision of Research and Innovation Akershus University Hospital Lørenskog Norway.ORCID 0000-0003-2114-3134
Torbjørn OmlandDepartment of Cardiology Division of Medicine Akershus University Hospital Lørenskog Norway.ORCID 0000-0002-6452-0369
Akershus University Hospital · NONorwegian University of Science and Technology · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Cardiac troponins represent a sensitive index of subclinical myocardial injury and are associated with increased risk of cardiovascular events in the general population. Despite positive associations with cardiovascular risk of both cardiac troponins and cigarette smoking, concentrations of cardiac troponin I measured by high-sensitivity assays (hs-cTnI) are paradoxically lower in current smokers than in never-smokers. The impact of smoking intensity and time from smoking cessation on hs-cTnI remains unknown. Methods and Results hs-cTnI concentrations were measured in 32028 subjects free from cardiovascular disease enrolled in the prospective, population-based HUNT (Trøndelag Health Study). Tobacco habits were self-reported and classified as never (n=14 559), former (n=14 248), and current (n=3221) smokers. Current smokers exhibited significantly lower concentrations of hs-cTnI than never-smokers (

Indexed as

Cardiovascular DiseasesTroponin IBiomarkersHumansProspective StudiesTobacco UseTroponin TBiomarkersTroponin ITroponin Tcardiac troponinscardiovascular diseasetobacco

Identifiers

PMID35001649
PMCPMC9238518
OpenAlexW4206519312

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.