Evidence map›Paper›PMID 35001531›Full record

ArticleJournal of diabetes2022

Relationship between creatinine to body weight ratios and diabetes mellitus: A Chinese cohort study.

Zhuangsen Chen, Yang Zou, Fan Yang, Xiao Han Ding, Changchun Cao, Haofei Hu, Xinyu Wang

Abstract read
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Article in Journal of diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhuangsen ChenDepartment of Endocrinology, Pingshan District People's Hospital of Shenzhen, Shenzhen, China.
Yang ZouDepartment of Cardiology, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.ORCID https://orcid.org/0000-0002-9373-928X
Fan YangDepartment of Endocrinology, Shenzhen Second People's Hospital, Shenzhen, China.ORCID https://orcid.org/0000-0001-7686-7020
Xiao Han DingDepartment of Endocrinology, Shenzhen Second People's Hospital, Shenzhen, China.
Changchun CaoDepartment of Rehabilitation, Shenzhen Dapeng New District Nan'ao People's Hospital, Shenzhen, China.
Haofei HuShenzhen University Health Science Center, Shenzhen, China.
Xinyu WangDepartment of Endocrinology, Shenzhen Second People's Hospital, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResearch on the relationship between creatinine to body weight ratios (Cre/BW ratios) and the prevalence of diabetes is still lacking. The intention of this research was to explore the potential relationship between Cre/BW ratio and diabetes prevalence in Chinese adults.

methodsThis retrospective study was conducted on 199 526 patients in the Chinese Rich Healthcare Group from 2010 to 2016. The participants were divided into four groups on the basis of the quartiles of the Cre/BW ratios. Multivariate multiple imputation and dummy variables were used to handle missing values. Multivariate regression analysis was applied to detect the relationship between Cre/BW and diabetes. A smoothing plot was also used to identify whether there were nonlinear relationships.

resultsAfter handling missing values and adjusting for potential confounders, the multivariate Cox regression analysis results showed that Cre/BW was inversely correlated with diabetes risk (hazard ratio [HR]: 0.268; 95% confidence interval [CI]: 0.229-0.314, p < 0.00001). For men, the HR of incident diabetes was 0.255 (95% CI: 0.212-0.307) and for women it was 0.297 (95% CI: 0.218-0.406). Moreover, sensitivity analysis confirmed the stability of the results. Furthermore, the smoothing plot revealed that there was a saturation effect between Cre/BW and the incidence of diabetes.

conclusionsThis study demonstrated that increased Cre/BW is negatively correlated with diabetes in Chinese adults. It also found that Cre/BW has a nonlinear relationship with the incidence of diabetes.

Indexed as

Diabetes MellitusDiabetes Mellitus, Type 2AdultBody WeightChinaCohort StudiesCreatinineFemaleHumansIncidenceMaleRetrospective StudiesRisk FactorsCreatininebody weightcreatininediabetes incidentdummy variablesmultiple imputationsnonlinearity体重哑变量多重插补糖尿病发病率肌酐非线性。

Identifiers

PMID35001531
PMCPMC9060036

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.