Evidence map›Paper›PMID 35001518›Full record

ArticleJournal of applied clinical medical physics2022

Investigation of Halcyon multi-leaf collimator model in Eclipse treatment planning system: A focus on the VMAT dose calculation with the Acuros XB algorithm.

Ryohei Miyasaka, SangYong Cho, Takuya Hiraoka, Kohei Chiba, Toru Kawachi, Tetsurou Katayose, Yuhi Suda, Ryusuke Hara

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ryohei MiyasakaDepartment of Radiation Oncology, Chiba Cancer Center, Chuo-ku, Chiba, Japan.
SangYong ChoDepartment of Radiation Oncology, Chiba Cancer Center, Chuo-ku, Chiba, Japan.
Takuya HiraokaDepartment of Radiation Oncology, Chiba Cancer Center, Chuo-ku, Chiba, Japan.
Kohei ChibaDepartment of Radiation Oncology, Chiba Cancer Center, Chuo-ku, Chiba, Japan.
Toru KawachiDepartment of Radiation Oncology, Chiba Cancer Center, Chuo-ku, Chiba, Japan.
Tetsurou KatayoseDepartment of Radiation Oncology, Chiba Cancer Center, Chuo-ku, Chiba, Japan.
Yuhi SudaDepartment of Radiotherapy, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Bunkyo-ku, Tokyo, Japan.
Ryusuke HaraDepartment of Radiation Oncology, Chiba Cancer Center, Chuo-ku, Chiba, Japan.
Chiba Cancer Center · JPTokyo Metropolitan Komagome Hospital · JP

Funding

Japan Society for the Promotion of Science JP19K17186
6 · The paper itself

Abstract

purposeThe dual-layer multi-leaf collimator (MLC) in Halcyon involves further complexities in the dose calculation process, because the leaf-tip transmission varies according to the leaf trailing pattern. For the volumetric modulated arc therapy (VMAT) treatment, the prescribed dose for the target volume can be sensitive to the leaf-tip transmission change. This report evaluates the dosimetric consequence due to the uncertainty of the dual-layer MLC model in Eclipse through the dose verifications for clinical VMAT. Additionally, the Halcyon leaf-tip model is empirically adjusted for the VMAT dose calculation with the Acuros XB. MATERIALS AND

methodsFor this evaluation, an in-house program that analyzes the leaf position in each layer was developed. Thirty-two clinical VMAT plans were edited into three leaf sequences: dual layer (original), proximal single layer, or distal single layer. All leaf sequences were verified using Delta4 according to the dose difference (DD) and the global gamma index (GI). To improve the VMAT dose calculation accuracy, the dosimetric leaf gap (DLG) was adjusted to minimize the DD in single-layer leaf sequences.

resultsThe mean of DD were -1.35%, -1.20%, and -1.34% in the dual-layer, proximal single-layer, and distal single-layer leaf sequences, respectively. The changes in the mean of DD between leaf sequences were within 0.2%. However, the calculated doses differed from the measured doses by approximately 1% in all leaf sequences. The tuned DLG was increased by 0.8 mm from the original DLG in Eclipse. When the tuned DLG was used in the dose calculation, the mean of DD neared 0% and GI with a criterion of 2%/2 mm yielded a pass rate of more than 98%.

conclusionNo significant change was confirmed in the dose calculation accuracy between the leaf sequences. Therefore, it is suggested that the dosimetric consequence due to the leaf trailing was negligibly small in clinical VMAT plans. The DLG tuning for Halcyon can be useful for reducing the dose calculation uncertainties in Eclipse VMAT and required in the commissioning for Acuros XB.

Indexed as

Radiotherapy, Intensity-ModulatedAlgorithmsHumansRadiometryRadiotherapy DosageRadiotherapy Planning, Computer-AssistedAcuros XBDLGHalcyonleaf trailingVMAT

Identifiers

PMID35001518
PMCPMC8906209
OpenAlexW4206263038

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.