ArticleInternational journal of cancer2022
Composite dietary antioxidant index and the risk of colorectal cancer: Findings from the Singapore Chinese Health Study.
Article in International journal of cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.
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Who cites it
106 citing papers in PubMed, 150 citations in OpenAlex.
- Association between overall dietary antioxidant capacity and lung cancer risk: findings from two observational studies.European journal of epidemiology · 2026Article
- From Biofortification to HT-29 Growth Inhibition: Selenium-Enriched Sunflower Sprouts Modulate Apoptosis- and Cell Cycle-Related Markers.Foods (Basel, Switzerland) · 2026Article
- Association Between Composite Dietary Antioxidant Index and Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome: Evidence From a Large Cohort in the UK Biobank.Food science & nutrition · 2026Article
- Nonlinear association between composite dietary antioxidant index and irritable bowel syndrome: insights from UK Biobank.BMC public health · 2026Article
- Review
- Interaction Between Composite Dietary Antioxidant Index and Alcohol Consumption on Cardiovascular Diseases: NHANES 2005-2018.Clinical cardiology · 2026Article
- Association between composite dietary antioxidant index and pulmonary function in middle-aged and older adults: results from two population-based studies.BMJ nutrition, prevention & health · 2026Article
- Association of the Composite Dietary Antioxidant Index with All-Cause, Cancer, and Cardiovascular Mortality: A Prospective Cohort Study.Food science & nutrition · 2026Article
- Inflammatory, antioxidant, and gut microbiota-related dietary indices and gastric cancer risk: a case-control study.Frontiers in nutrition · 2026Article
- Association of composite dietary antioxidant index with menopause age and reproductive lifespan in NHANES 1999-2018: A Cross-Sectional study.Scientific reports · 2025Article
- Global burden of colorectal cancer in 2022 and projections to 2050: incidence and mortality estimates from GLOBOCAN.BMC cancer · 2025Article
- Assessing the Impact of Composite Dietary Antioxidant Index on Gastric Cancer Risk: A Case-Control Study in Southeast China.Nutrients · 2025Article
- The mediating role of BMI in the association between composite dietary antioxidant index and infertility in women: a nationwide population-based study.BMC women's health · 2025Article
- Linear association between the composite dietary antioxidant index and the prevalence of sarcopenia in metabolic dysfunction-associated steatotic liver disease.Lipids in health and disease · 2025Article
- Predicting depression risk with machine learning models: identifying familial, personal, and dietary determinants.BMC psychiatry · 2025Article
- Cancer Burden Across The South East Asia Nation (ASEAN) in 2022.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Predictive capabilities of polygenic scores in an East-Asian population-based cohort: the Singapore Chinese health study.Communications biology · 2025Article
- Composite dietary antioxidant index and lung cancer risk: insights from the UK biobank.BMC public health · 2025Article
- Association of an antioxidant-rich diet with all-cause and cardiovascular mortality in hypertensive patients: A prospective study.Medicine · 2025Observational
- Composite dietary antioxidant index is nonlinearly associated with low muscle mass in the general US population: findings from NHANES 2001-2018.Nutrition journal · 2025Article
46 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
Abstract
Colorectal cancer (CRC) is a major contributor to cancer death globally. Several studies showed some protections by certain individual dietary antioxidants against CRC development. Epidemiologic data on the composite dietary antioxidant index (CDAI) in relation to CRC risk are sparse. Using the Singapore Chinese Health Study, an ongoing prospective cohort consisting of 61 321 cancer-free participants aged 45 to 74 years at baseline, a food-based CDAI was calculated according to a previously established and validated method that included six food-sourced antioxidants including vitamins A, C and E, manganese, selenium and zinc. Cox proportional hazard regression method was used to estimate the hazard ratios (HRs) and their 95% confidence intervals (CIs) for CRC associated with various levels of CDAI with adjustment for multiple potential confounders. After an average of 17.5 years of follow-up, 2140 participants developed CRC. HRs (95% CIs) of CRC for quartiles 2, 3 and 4 of CDAI were 0.94 (0.83-1.07), 0.86 (0.75-1.00) and 0.80 (0.66-0.98), respectively, compared to the lowest quartile (P
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.