Evidence map›Paper›PMID 35001220›Full record

ArticleVisual computing for industry, biomedicine, and art2022

Spatially resolved transcriptomics in immersive environments.

Denis Bienroth, Hieu T Nim, Dimitar Garkov, Karsten Klein, Sabrina Jaeger-Honz, Mirana Ramialison, Falk Schreiber

Abstract read
In one paragraph

Article in Visual computing for industry, biomedicine, and art, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Insights Into Spatial Transcriptomics: Exploring Recent Technical Developments and Their Diverse Applications.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  2. Article
  3. Article
  4. Beyond the horizon: immersive developments for animal ecology research.Visual computing for industry, biomedicine, and art · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Denis BienrothDepartment of Computer and Information Science, University of Konstanz, Konstanz, Germany.
Hieu T NimCell Biology, Murdoch Children's Research Institute, Parkville, Melbourne, VIC, Australia.
Dimitar GarkovDepartment of Computer and Information Science, University of Konstanz, Konstanz, Germany.
Karsten KleinDepartment of Computer and Information Science, University of Konstanz, Konstanz, Germany.ORCID http://orcid.org/0000-0002-8345-5806
Sabrina Jaeger-HonzDepartment of Computer and Information Science, University of Konstanz, Konstanz, Germany.
Mirana RamialisonCell Biology, Murdoch Children's Research Institute, Parkville, Melbourne, VIC, Australia. mirana.ramialison@monash.edu.
Falk SchreiberDepartment of Computer and Information Science, University of Konstanz, Konstanz, Germany. falk.schreiber@uni-konstanz.de.

Funding

ARC Discovery Project 190102771Deutsche Forschungsgemeinschaft 251654672Deutsche Forschungsgemeinschaft 422037984NH & MRC Career Development Fellowship
6 · The paper itself

Abstract

Spatially resolved transcriptomics is an emerging class of high-throughput technologies that enable biologists to systematically investigate the expression of genes along with spatial information. Upon data acquisition, one major hurdle is the subsequent interpretation and visualization of the datasets acquired. To address this challenge, VR-Cardiomics is presented, which is a novel data visualization system with interactive functionalities designed to help biologists interpret spatially resolved transcriptomic datasets. By implementing the system in two separate immersive environments, fish tank virtual reality (FTVR) and head-mounted display virtual reality (HMD-VR), biologists can interact with the data in novel ways not previously possible, such as visually exploring the gene expression patterns of an organ, and comparing genes based on their 3D expression profiles. Further, a biologist-driven use-case is presented, in which immersive environments facilitate biologists to explore and compare the heart expression profiles of different genes.

Indexed as

Fish tank virtual realityHead-mounted displayImmersive analyticsImmersive environmentSpatially-resolved transcriptomicsSpatial transcriptomicsVirtual reality

Identifiers

PMID35001220
PMCPMC8743310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.