Evidence map›Paper›PMID 35001214›Full record

ArticleClinical oral investigations2022

Physicochemical and biological properties of experimental dental adhesives doped with a guanidine-based polymer: an in vitro study.

Lucas Bonfanti Silvestrin, Isadora Martini Garcia, Fernanda Visioli, Fabrício Mezzomo Collares, Vicente Castelo Branco Leitune

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Evolution of Dental Resin Adhesives-A Comprehensive Review.Journal of functional biomaterials · 2025
    Review
  2. A Multifunctional Dental Resin Composite with Sr-N-Doped TiOInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lucas Bonfanti SilvestrinDepartment of Dental Materials, School of Dentistry, Federal University of Rio Grande do Sul, Ramiro Barcelos Street, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil.ORCID https://orcid.org/0000-0002-4408-0087
Isadora Martini GarciaDepartment of Dental Materials, School of Dentistry, Federal University of Rio Grande do Sul, Ramiro Barcelos Street, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil.ORCID https://orcid.org/0000-0002-7388-0200
Fernanda VisioliOral Pathology Departament, School of Dentistry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil.ORCID https://orcid.org/0000-0002-4033-8431
Fabrício Mezzomo CollaresDepartment of Dental Materials, School of Dentistry, Federal University of Rio Grande do Sul, Ramiro Barcelos Street, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil.ORCID https://orcid.org/0000-0002-1382-0150
Vicente Castelo Branco LeituneDepartment of Dental Materials, School of Dentistry, Federal University of Rio Grande do Sul, Ramiro Barcelos Street, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil. vicente.leitune@ufrgs.br.ORCID http://orcid.org/0000-0002-5415-1731
Universidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of this study is to formulate experimental dental adhesives with different polyhexamethylene guanidine hydrochloride concentrations (PHMGH) and evaluate their physical, chemical, and biological properties. MATERIALS AND

methodsThe experimental adhesives were formulated with 0 (control, G

resultsThere were no differences among groups for DC%, ΔKHN%, and UTS (p > 0.05%). There were no differences between each PHMGH-doped adhesive compared to G

conclusionsThe adhesive with 2 wt.% of PHMGH showed the highest antibacterial activity, without affecting the physicochemical properties and cytotoxicity, besides conferring stability for the dental adhesion. CLINICAL RELEVANCE: PHMGH, a positively charged polymer, conveyed antibacterial activity to dental adhesives. Furthermore, it did not negatively affect the essential physicochemical and biocompatibility properties of the adhesives. More importantly, the incorporation of PHMGH provided stability for the μ-TBS compared to the control group without this additive.

Indexed as

Dental BondingResin CementsAdhesivesDental CementsDentinDentin-Bonding AgentsGuanidineMaterials TestingPolymersTensile StrengthAdhesivesDental CementsDentin-Bonding AgentsGuanidinePolymersResin CementsAnti-bacterial agentsDental bondingDental cariesOral biofilmPolymerization

Identifiers

PMID35001214
OpenAlexW4205951207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.