Evidence map›Paper›PMID 35001210›Full record

ReviewCell and tissue research2022

Stem cell transplantation as a progressing treatment for retinitis pigmentosa.

Sedighe Hosseini Shabanan, Homa Seyedmirzaei, Alona Barnea, Sara Hanaei, Nima Rezaei

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cell and tissue research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. An update on visual prosthesis.International journal of retina and vitreous · 2023
    Review
  8. Genome editing in the treatment of ocular diseases.Experimental & molecular medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Sedighe Hosseini ShabananSchool of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Homa SeyedmirzaeiSchool of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Alona BarneaLaboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY, USA.
Sara HanaeiSchool of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Nima RezaeiSchool of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran. rezaei_nima@tums.ac.ir.ORCID http://orcid.org/0000-0002-3836-1827
Universal Scientific Education and Research Network · IREducation and Research Network · INRockefeller University · USTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinal degenerative diseases such as retinitis pigmentosa (RP) are of the major causes of vision loss in developed countries. Despite the unclear pathophysiology, treatment methods have been investigated vastly in the past decades. This review article mainly discusses the advances in application of stem cell and progenitor transplantation for retinitis pigmentosa. Stem cell sources such as mesenchymal stem cells, embryonic stem cells, induced pluripotent stem cells, neural stem cells, retinal progenitor cells, and olfactory ensheathing cells are discussed separately in addition to a brief description of two approaches for treatment of early-stage RP, including gene therapy and nutritional therapy.

Indexed as

Induced Pluripotent Stem CellsRetinal DegenerationRetinitis PigmentosaHumansRetinaStem Cell TransplantationCell therapyGene therapyNutritional therapyRetinitis pigmentosaStem cell transplantation

Identifiers

PMID35001210
OpenAlexW4205542815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.