ArticleWorld journal of urology2022
Use of high-resolution micro-ultrasound to predict extraprostatic extension of prostate cancer prior to surgery: a prospective single-institutional study.
Article in World journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- The Role of Micro-Ultrasound in Prostate Cancer Detection.Current urology reports · 2026Review
- From Detection to Surveillance: The Evolving Role of Micro-Ultrasound in Prostate Cancer.Diagnostics (Basel, Switzerland) · 2026Review
- Development of ultrasonography for the detection of prostate cancer.Journal of medical ultrasonics (2001) · 2026Review
- Article
- Micro-ultrasound for prostate cancer.Nature reviews. Urology · 2026Review
- Review
- Micro-Ultrasound in the Detection of Clinically Significant Prostate Cancer: A Comprehensive Review and Comparison with Multiparametric MRI.Tomography (Ann Arbor, Mich.) · 2025Review
- Intraoperative technologies to assess margin status during radical prostatectomy - a narrative review.Prostate cancer and prostatic diseases · 2025Review
- The Impact of Omitting Contralateral Systematic Biopsy on the Surgical Planning of Patients with a Unilateral Suspicious Lesion on Magnetic Resonance Imaging Undergoing Robot-assisted Radical Prostatectomy for Prostate Cancer.European urology open science · 2024Article
- Is multiparametric MRI always needed in biopsy-naïve patients with abnormal digital rectal examination? A single-institutional experience combining clinical and micro-ultrasonography-based factors to optimize prostate cancer detection.World journal of urology · 2024Article
- The diagnostic accuracy of micro-ultrasound for prostate cancer diagnosis: a review.World journal of urology · 2023Review
- Diagnostic accuracy of multiparametric MRI- and microultrasound-targeted biopsy in biopsy-naïve patients with a PI-RADS 5 lesion: a single-institutional study.World journal of urology · 2023Article
- Prostatic high-resolution micro-ultrasound: an attractive step-forward in the management of prostate cancer patients.Prostate cancer and prostatic diseases · 2023Review
- Review
- Article
- Side-specific, Microultrasound-based Nomogram for the Prediction of Extracapsular Extension in Prostate Cancer.European urology open science · 2023Article
- Micro-Ultrasound in the Diagnosis and Staging of Prostate and Bladder Cancer: A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2022Review
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aim to evaluate the accuracy of micro-ultrasound (microUS) in predicting extraprostatic extension (EPE) of Prostate Cancer (PCa) prior to surgery.
methodsPatients with biopsy-proven PCa scheduled for robot-assisted radical prostatectomy (RARP) were prospectively recruited. The following MRI-derived microUS features were evaluated: capsular bulging, visible breach of the prostate capsule (visible extracapsular extension; ECE), presence of hypoechoic halo, and obliteration of the vesicle-prostatic angle. The ability of each feature to predict EPE was determined.
resultsOverall, data from 140 patients were examined. All predictors were associated with non-organ-confined disease (p < 0.001). Final pathology showed that 79 patients (56.4%) had a pT2 disease and 61 (43.3%) ≥ pT3. Rate of non-organ-confined disease increased from 44% in those individuals with only 1 predictor (OR 7.71) to 92.3% in those where 4 predictors (OR 72.00) were simultaneously observed. The multivariate logistic regression model including clinical parameters showed an area under the curve (AUC) of 82.3% as compared to an AUC of 87.6% for the model including both clinical and microUS parameters. Presence of ECE at microUS predicted EPE with a sensitivity of 72.1% and a specificity of 88%, a negative predictive value of 80.5% and positive predictive value of 83.0%, with an AUC of 80.4%.
conclusionsMicroUS can accurately predict EPE at the final pathology report in patients scheduled for RARP.
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