Evidence map›Paper›PMID 35000899›Full record

ArticleEuropean journal of endocrinology2022

Italian Association of Clinical Endocrinologists (AME) and International Chapter of Clinical Endocrinology (ICCE). Position statement for clinical practice: prolactin-secreting tumors.

Renato Cozzi, Maria Rosaria Ambrosio, Roberto Attanasio, Claudia Battista, Alessandro Bozzao, Marco Caputo, Enrica Ciccarelli, Laura De Marinis, Ernesto De Menis, Marco Faustini Fustini and 12 more

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in European journal of endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 4 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 4 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Italian Guidelines for the Management of Prolactinomas.Endocrine, metabolic & immune disorders drug targets · 2023
    Guideline
  5. Article
  6. Review
  7. Journal of the Endocrine Society · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Prolactinomas treated with dopaminergic agonists: behavior in different moments of life.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 17 institutions in 4 countries.

Renato CozziDivision of Endocrinology, Niguarda Hospital, Milan, Italy.
Maria Rosaria AmbrosioSection of Endocrinology and Internal Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Roberto AttanasioAME Scientific Committee, Milan, Italy.ORCID 0000-0002-1417-287X
Claudia BattistaEndocrinology Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo (FG), Italy.
Alessandro BozzaoNeuroradiology, S. Andrea Hospital, NESMOS Department (Neuroscience, Mental Health, Sensorial Organs), Sapienza University of Rome, Rome, Italy.
Marco CaputoLaboratorio Analisi Cliniche e Microbiologia, Synlab SRL, Calenzano, Florence, Italy.
Enrica CiccarelliEndocrinology, Ospedale Martini, ASL Città di Torino, Turin, Italy.
Laura De MarinisPituitary Unit, Department of Endocrinology, Catholic University of the Sacred Heart, School of Medicine, Rome, Italy.
Ernesto De MenisInternal Medicine 2, Treviso Hospital, Treviso, Italy.
Marco Faustini FustiniIRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Franco GrimaldiAME President, Endocrinology and Metabolism Unit, University Hospital S. Maria della Misericordia, Udine, Italy.
Andrea LaniaDepartment of Biomedical Sciences, Endocrinology Unit, Rozzano, Italy.
Giovanni LasioDepartment of Neurosurgery, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
Francesco LogolusoEndocrinology Unit, Bisceglie Hospital, ASLBT, Bisceglie, Italy.
Marco LosaDepartment of Neurosurgery and Gamma Knife Radiosurgery, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Milan, Italy.
Pietro MaffeiDepartment of Medicine (DIMED), 3rd Medical Clinic, Padua University Hospital, Padua, Italy.
Davide MilaniDepartment of Neurosurgery, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
Maurizio PoggiEndocrinology, Department of Clinical and Molecular Medicine, S. Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Michele ZiniEndocrinology Unit, Azienda Ospedaliera S. Maria Nuova IRCCS, Reggio Emilia, Italy.
Laurence KatznelsonDepartment of Medicine, Stanford University Hospital, Stanford, CA, USA.
Anton LugerDivision of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria.
Catalina Poiana'Carol Davila' University of Medicine and Pharmacy - Endocrinology, "C.I. Parhon" National Institute of Endocrinology - Pituitary and Neuroendocrine Disorders, Bucharest, Romania.
Humanitas University · ITSapienza University of Rome · ITAzienda Ospedaliera S.Maria · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITCa' Foncello Hospital · ITCarol Davila University of Medicine and Pharmacy · ROCasa Sollievo della Sofferenza · ITIstituto delle Scienze Neurologiche di Bologna · ITMedical University of Vienna · ATOspedale degli Infermi · ITOspedale Martini · ITOspedale Santa Maria della Misericordia di Udine · ITStanford University · USUniversità Cattolica del Sacro Cuore · ITUniversity of Ferrara · ITUniversity of Padua · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prolactinomas are the most frequent pituitary adenomas. Prolactinoma may occur in different clinical settings and always require an individually tailored approach. This is the reason why a panel of Italian neuroendocrine experts was charged with the task to provide indications for the diagnostic and therapeutic approaches that can be easily applied in different contexts. The document provides 15 recommendations for diagnosis and 54 recommendations for treatment, issued according to the GRADE system. The level of agreement among panel members was formally evaluated by RAND-UCLA methodology. In the last century, prolactinomas represented the paradigm of pituitary tumors for which the development of highly effective drugs obtained the best results, allowing to avoid neurosurgery in most cases. The impressive improvement of neurosurgical endoscopic techniques allows a far better definition of the tumoral tissue during surgery and the remission of endocrine symptoms in many patients with pituitary tumors. Consequently, this refinement of neurosurgery is changing the therapeutic strategy in prolactinomas, allowing the definitive cure of some patients with permanent discontinuation of medical therapy.

Indexed as

ChildConsensusDopamine AgentsEndocrinologyEvidence-Based MedicineFemaleHumansHyperprolactinemiaItalyMaleNeurosurgical ProceduresPituitary NeoplasmsPregnancyProlactinomaRadiotherapyDopamine Agents

Identifiers

PMID35000899
PMCPMC8859924
OpenAlexW4205736689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.