Evidence map›Paper›PMID 35000670›Full record

ArticleBMB reports2022

Exercise-induced beige adipogenesis of iWAT in Cidea reporter mice.

Jin Kyung Kim, Hye Sun Go, Sol Pin Kim, Il Yong Kim, Yun Hee Lee, Seung Hyun Oh, Ho Lee, Je Kyung Seong

Erratum issuedOpen access · goldAbstract readNews
PubMed Full text at PMC
In one paragraph

Article in BMB reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jin Kyung KimLaboratory of Developmental Biology and Genomics, College of Veterinary Medicine, BK21 Plus Program for Advanced Veterinary Science, Research Institute for Veterinary Science Seoul National University, Seoul 08826; Korea Mouse Phenotyping Center (KMPC), Seoul 08826, Korea.
Hye Sun GoKorea Mouse Phenotyping Center (KMPC), Seoul 08826, Korea.
Sol Pin KimKorea Mouse Phenotyping Center (KMPC), Seoul 08826, Korea.
Il Yong KimLaboratory of Developmental Biology and Genomics, College of Veterinary Medicine, BK21 Plus Program for Advanced Veterinary Science, Research Institute for Veterinary Science Seoul National University, Seoul 08826; Korea Mouse Phenotyping Center (KMPC), Seoul 08826, Korea.
Yun Hee LeeKorea Mouse Phenotyping Center (KMPC), Seoul 08826; College of Pharmacy, Seoul National University, Seoul 08826, Korea.
Seung Hyun OhKorea Mouse Phenotyping Center (KMPC), Seoul 08826; College of Pharmacy, Gachon University, Incheon 21936, Korea.
Ho LeeKorea Mouse Phenotyping Center (KMPC), Seoul 08826; National Cancer Center, Goyang 10408, Korea.
Je Kyung SeongLaboratory of Developmental Biology and Genomics, College of Veterinary Medicine, BK21 Plus Program for Advanced Veterinary Science, Research Institute for Veterinary Science Seoul National University, Seoul 08826; Korea Mouse Phenotyping Center (KMPC), Seoul 08826, Korea.
Seoul National University · KRGachon University · KRNational Cancer Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is caused by an imbalance between energy intake and energy expenditure. Exercise is attracting attention as one of the ways to treat obesity. Exercise induces 'beige adipogenesis' in white adipose tissue, increasing total energy expenditure via energy dissipation in the form of heat. Also, beige adipogenesis can be induced by treatment with a beta-adrenergic receptor agonist. We developed a Cidea-dual reporter mouse (Cidea-P2ALuc2-T2A-tdTomato, Luciferase/tdTomato) model to trace and measure beige adipogenesis in vivo. As a result, both exercise and injection of beta-adrenergic receptor agonist induced beige adipogenesis and was detected through fluorescence and luminescence. We confirmed that exercise and beta-adrenergic receptor agonist induce beige adipogenesis in Cidea-dual reporter mouse, which will be widely used for detecting beige adipogenesis in vivo. [BMB Reports 2022; 55(4): 187-191].

Indexed as

AdipogenesisAdipose Tissue, WhiteAnimalsApoptosis Regulatory ProteinsMiceObesitySignal TransductionApoptosis Regulatory ProteinsCidea protein, mouse

Identifiers

PMID35000670
PMCPMC9058471
OpenAlexW4206847408

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.