Observational studyCritical care (London, England)2022
Hyperoxemia in postsurgical sepsis/septic shock patients is associated with reduced mortality.
Observational study in Critical care (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Genome-wide association study of susceptibility to acute respiratory distress syndrome.EBioMedicine · 2025Pooled it
- Development and validation of a predictive model for septic shock in maternal sepsis: a retrospective cohort study in a single referral center.BMC pregnancy and childbirth · 2026Article
- Lung function impairment and risk of sepsis and sepsis-related mortality: a large cohort study with over 310,000 participants.Science China. Life sciences · 2026Article
- The correlation study between post-surgery oxygen partial pressure level and prognosis of patients with sepsis during hospitalization.Medicine · 2025Observational
- [First 24-hour arterial oxygen partial pressure is correlated with mortality in ICU patients with acute kidney injury: an analysis based on MIMIC-IV database].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- OPTIMAL PAO 2 IS 130-160 MMHG IN THE FIRST WEEK FOR SEPSIS PATIENTS IN ICU: A RETROSPECTIVE COHORT STUDY BASED ON MIMIC-IV DATABASE.Shock (Augusta, Ga.) · 2025Article
- Identifying sepsis susceptibility genes in post-surgical patients using an artificial intelligence approach.Frontiers in medicine · 2025Article
- Chest radiographs in acute respiratory distress syndrome: an Achilles' heel of the Berlin criteria?Frontiers in medicine · 2025Article
- Oxygen targets in patients with septic shock: a retrospective cohort study on the association between hyperoxia and mortality.Frontiers in medicine · 2025Article
- The dysfunction of complement and coagulation in diseases: the implications for the therapeutic interventions.MedComm · 2024Review
- Analysis of fecal microbiota and related clinical indicators in ICU patients with sepsis.Heliyon · 2024Article
- Post-operative sepsis-induced acute respiratory distress syndrome: risk factors for a life-threatening complication.Frontiers in medicine · 2024Article
- Review
- Hyperoxia in critically ill patients with sepsis and septic shock: a systematic review.Journal of anesthesia, analgesia and critical care · 2023Review
- An early warning model for predicting major adverse kidney events within 30 days in sepsis patients.Frontiers in medicine · 2023Article
- Evaluation of Platelet Distribution Width as an Early Predictor of Acute Kidney Injury in Extensive Burn Patients.Emergency medicine international · 2023Article
- Effect of sex on the association between arterial partial pressure of oxygen and in-hospital mortality in ICU patients with cardiogenic shock: a retrospective cohort study.Annals of translational medicine · 2022Article
- Ibrutinib Prevents Acute Lung Injury via Multi-Targeting BTK, FLT3 and EGFR in Mice.International journal of molecular sciences · 2022Article
- Time-varying intensity of oxygen exposure is associated with mortality in critically ill patients with mechanical ventilation.Critical care (London, England) · 2022Article
- Reply to "Hyperoxemia in postsurgical sepsis/septic shock patients is associated with reduced mortality".Critical care (London, England) · 2022Article
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Authors and funding
18 authors at 5 institutions in 4 countries.
Funding
Abstract
backgroundDespite growing interest in treatment strategies that limit oxygen exposure in ICU patients, no studies have compared conservative oxygen with standard oxygen in postsurgical patients with sepsis/septic shock, although there are indications that it may improve outcomes. It has been proven that high partial pressure of oxygen in arterial blood (PaO
methodsWe performed a secondary analysis of a prospective observational study in 454 patients who underwent major surgery admitted into a single ICU. Patients were stratified in two groups whether they had hyperoxemia, defined as PaO
resultsIn patients with PaO
conclusionsOxygenation with a PaO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.