Evidence map›Paper›PMID 35000503›Full record

ArticleVascular medicine (London, England)2022

Cardiovascular manifestations of hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders.

Eman R Rashed, Tania Ruiz Maya, Jennifer Black, Veronica Fettig, Daniella Kadian-Dodov, Jeffrey W Olin, Lakshmi Mehta, Bruce D Gelb, Amy R Kontorovich

Open access · greenAbstract read
In one paragraph

Article in Vascular medicine (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Immune Mechanisms of Heart Valve Development, Homeostasis, and Disease.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Echocardiographic Assessment in Patients with Vascular Ehlers-Danlos Syndrome: Insights from an Unexplored Field.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Hypermobility spectrum disorders: A review.Rheumatology and immunology research · 2023
    Article
  17. Current Understanding of Aortic Dissection.Life (Basel, Switzerland) · 2022
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Eman R RashedThe Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Tania Ruiz MayaThe Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jennifer BlackDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Veronica FettigThe Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Daniella Kadian-DodovThe Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jeffrey W OlinThe Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lakshmi MehtaDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Bruce D GelbDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Amy R KontorovichThe Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-7400-5507
Cardiovascular Institute of the South · USIcahn School of Medicine at Mount Sinai · USChild Health and Development Institute · US

Funding

Pediatric Heart Disease: Getting from Mutations to TherapeuticsR35HL135742 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GELB, BRUCE D · 2017 to 2023
$6.1M
Elucidation of the role of human genetic factors underlying viral myocarditis susceptibilityK23HL140083 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KONTOROVICH, AMY R. · 2018 to 2022
$952k
NHLBI NIH HHS K23 HL140083NHLBI NIH HHS R35 HL135742
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Ehlers-Danlos SyndromeJoint InstabilityMitral Valve ProlapseAdultEchocardiographyFemaleHumansMaleaortic diseasecervical artery dissection (CeAD)Ehlers–Danlos syndromegeneticsspontaneous coronary artery dissection (SCAD)

Identifiers

PMID35000503
PMCPMC9677229
OpenAlexW4205825998

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.