ArticleNeurospine2021
Upper Cervical Compression Myelopathy Caused by the Retro-Odontoid Pseudotumor With Degenerative Osteoarthritis and Calcium Pyrophosphate Dihydrate Disease: A Case Report and Literature Review.
Article in Neurospine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Risk factors for the development of retro-odontoid pseudotumor in non-rheumatoid arthritis patients with atlantoaxial subluxation: a multicenter cross-sectional study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- CPPD-related basilar impression with vertebral artery dissection and subsequent subarachnoid hemorrhage: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Retro-Odontoid Pseudotumor in Atlantoaxial Instability: Insights Into Presence, Subtypes, and Postoperative Regression.Neurospine · 2025Article
- Novel Approach to Retro-Odontoid Pseudotumor Resection without Atlantoaxial Dislocation.The American journal of case reports · 2025Article
- Acute myelopathy caused by granuloma formation secondary to gelatin sponge: A case report of a rare complication.Surgical neurology international · 2025Article
- Periodontoid Pseudotumor with Respiratory Arrest.Journal of emergencies, trauma, and shockArticle
- Diagnostic Challenge of a Tumor-mimicking Spinal Pseudogout Lesion: Case Report and Literature Review.Cancer diagnosis & prognosisArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The retro-odontoid pseudotumor is often concurrent with atlantoaxial subluxation (AAS). Therefore, the pseudotumor is relatively common in rheumatoid arthritis (RA) but rare in primary osteoarthritis (OA). This is a case report of an elderly male patient suffering from neck pain and compression myelopathy caused by the craniocervical pseudotumor with OA but without atlantoaxial instability. He had long-lasting peripheral and spinal pain treated by nonsteroidal anti-inflammatory drugs. Imaging found upper cervical spondylosis without AAS or dynamic instability but with periodontoid calcifications and ossifications, suggesting calcium pyrophosphate dihydrate (CPPD) crystal deposition. Based on a comprehensive literature search and review, CPPD disease around the atlantodental joint is a possible contributor to secondary OA development and retro-odontoid pannus formation through chronic inflammation, which can be enough severe to induce compression myelopathy in non-RA patients without AAS. The global increase in the aged population advises caution regarding more prevalent upper cervical spine disorders associated with OA and CPPD.
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Registered trials
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