Evidence map›Paper›PMID 35000177›Full record

ReviewEnvironmental science and pollution research international2022

Current understandings and perspectives of petroleum hydrocarbons in Alzheimer's disease and Parkinson's disease: a global concern.

Rajalakshmi Rajendran, Roshni Pushpa Ragavan, Abdullah G Al-Sehemi, Md Sahab Uddin, Lotfi Aleya, Bijo Mathew

Abstract readReview
PubMed Publisher
In one paragraph

Review in Environmental science and pollution research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 5 countries.

Rajalakshmi RajendranDepartment of Pharmacy Practice, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi, 682041, Kerala, India.
Roshni Pushpa RagavanResearch Center for Advanced Materials Science, King Khalid University, Abha, 61413, Saudi Arabia. roshnipr@aims.amrita.edu.
Abdullah G Al-SehemiResearch Center for Advanced Materials Science, King Khalid University, Abha, 61413, Saudi Arabia.
Md Sahab UddinDepartment of Pharmacy, Southeast University, Dhaka, Bangladesh.
Lotfi AleyaLaboratoire Chrono-Environment, CNRS6249, Universite de Bourgogne Franche-Comte, Besancon, France.
Bijo MathewDepartment of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, 682 041, India. bijomathew@aims.amrita.edu.ORCID http://orcid.org/0000-0002-6658-4497
King Khalid University · SAAims Community College · USAmrita Vishwa Vidyapeetham · INCentre National de la Recherche Scientifique · FRSoutheast University · BD

Funding

king khalid university for funding this work through the research group project under grant number r.g.p.2/96/42. Grant number R.G.P.2/96/42.
6 · The paper itself

Abstract

Over the last few decades, the global prevalence of neurodevelopmental and neurodegenerative illnesses has risen rapidly. Although the aetiology remains unclear, evidence is mounting that exposure to persistent hydrocarbon pollutants is a substantial risk factor, predisposing a person to neurological diseases later in life. Epidemiological studies correlate environmental hydrocarbon exposure to brain disorders including neuropathies, cognitive, motor and sensory impairments; neurodevelopmental disorders like autism spectrum disorder (ASD); and neurodegenerative disorders like Alzheimer's disease (AD) and Parkinson's disease (PD). Particulate matter, benzene, toluene, ethylbenzene, xylenes, polycyclic aromatic hydrocarbons and endocrine-disrupting chemicals have all been linked to neurodevelopmental problems in all class of people. There is mounting evidence that supports the prevalence of petroleum hydrocarbon becoming neurotoxic and being involved in the pathogenesis of AD and PD. More study is needed to fully comprehend the scope of these problems in the context of unconventional oil and natural gas. This review summarises in vitro, animal and epidemiological research on the genesis of neurodegenerative disorders, highlighting evidence that supports inexorable role of hazardous hydrocarbon exposure in the pathophysiology of AD and PD. In this review, we offer a summary of the existing evidence gathered through a Medline literature search of systematic reviews and meta-analyses of the most important epidemiological studies published so far.

Indexed as

Alzheimer DiseaseAutism Spectrum DisorderParkinson DiseasePetroleumAnimalsHumansHydrocarbonsSystematic Reviews as TopicHydrocarbonsPetroleumAlzheimer’s diseaseAryl hydrocarbon receptorNeurodegenerationParkinson’s diseasePetroleum hydrocarbon

Identifiers

PMID35000177
OpenAlexW4206234165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.