Evidence map›Paper›PMID 35000115›Full record

ArticleIrish journal of medical science2022

Clinical characteristics of two groups commonly referred to an Irish hypertension service-patients with resistant hypertension and young adults with hypertension.

Cormac Kennedy, Osama Ali, Richard Farnan, John Stinson, Ahmed Gabr, Mary Hall, Patricia O'Connor, Martina Hennessy, Michael Barry

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In one paragraph

Article in Irish journal of medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Hypertension Treatment with Angiotensin Receptor Blockers and Other Antihypertensive Agents: A Real-World Registry from a High-Volume Specialized Center Over TwoDecades.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Cormac KennedyDepartment of Pharmacology and Therapeutics, Trinity College, Dublin 8, Ireland. kennec30@tcd.ie.ORCID http://orcid.org/0000-0002-2577-0242
Osama AliSt James Hospital, Dublin 8, Ireland.
Richard FarnanDepartment of Pharmacology and Therapeutics, Trinity College, Dublin 8, Ireland.
John StinsonSt James Hospital, Dublin 8, Ireland.
Ahmed GabrSt James Hospital, Dublin 8, Ireland.
Mary HallSt James Hospital, Dublin 8, Ireland.
Patricia O'ConnorDepartment of Pharmacology and Therapeutics, Trinity College, Dublin 8, Ireland.
Martina HennessyDepartment of Pharmacology and Therapeutics, Trinity College, Dublin 8, Ireland.
Michael BarryDepartment of Pharmacology and Therapeutics, Trinity College, Dublin 8, Ireland.
St. James's Hospital · IETrinity College Dublin · IELeo Pharma (Ireland) · IETrinity College · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of hypertension is primarily performed in primary care settings in many health systems. However, two groups of patients often require specialist input: patients with resistant hypertension (RH) and young adults with hypertension.

aimsTo elucidate these groups by examining the characteristics of patients attending an Irish hypertension service, thus informing future management of hypertension.

methodsPatients were recruited at consecutive hypertension clinics at St James Hospital, Dublin from July to September 2019. Following patient consent, patient data were recorded to identify patient characteristics as well as the results of investigations, blood pressure (BP) measurements and the anti-hypertensive treatment of the study participants which were then analysed.

resultsTwo hundred thirty-six patients were included in the study. Compared to those without RH, the RH group were more likely to be obese (OR 2.59 [95% CI 1.06 to 6.33]), to have cardiovascular disease (OR 3.07 [95% CI 1.56 to 6.02]) and to have a non-dipping BP pattern (OR 3.86 [95% CI 1.57 to 9.47]). Young adults comprised 27% of the cohort. Forty-seven percent of these patients were obese, 15.9% had hypertension in pregnancy and 22.2% had chronic headaches. Despite being prescribed less anti-hypertensives (1.41 vs 2.28; p < 0.05), the majority of young patients had a BP less than 140/90 mmHg, comparing favourably with older patients (OR 2.25 [95% CI 1.20 to 4.27]).

conclusionThis contemporary study highlights the high prevalence of obesity among RH patients and young adults with hypertension. Findings suggest that programs to combat hypertension must include interventions to address obesity.

Indexed as

Cardiovascular DiseasesHypertensionAntihypertensive AgentsBlood PressureHumansObesityPrevalenceYoung AdultAntihypertensive AgentsHypertension clinicObesityResistant hypertensionYoung adults

Identifiers

PMID35000115
OpenAlexW4205561276

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.