Evidence map›Paper›PMID 35000032›Full record

ArticleClinical and experimental nephrology2022

Cost-effectiveness of mass screening for dipstick hematuria in Japan.

Reiko Okubo, Shu-Ling Hoshi, Tomokazu Kimura, Masahide Kondo, Koichi Asahi, Chiho Iseki, Shouichi Fujimoto, Ichiei Narita, Hiroyuki Nishiyama, Kunihiro Yamagata and 1 more

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In one paragraph

Article in Clinical and experimental nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Reiko OkuboDepartment of Health Care Policy and Health Economics, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8577, Japan.
Shu-Ling HoshiDepartment of Health Care Policy and Health Economics, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8577, Japan.
Tomokazu KimuraDepartment of Urology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Masahide KondoDepartment of Health Care Policy and Health Economics, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8577, Japan. mkondo@md.tsukuba.ac.jp.ORCID http://orcid.org/0000-0001-9125-2040
Koichi AsahiDivision of Nephrology and Hypertension, Department of Internal Medicine, Iwate Medical University School of Medicine, Yahaba, Japan.
Chiho IsekiOkinawa Heart and Renal Association (OHRA), Naha, Okinawa, Japan.
Shouichi FujimotoDepartment of Hemovascular Medicine and Artificial Organs, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
Ichiei NaritaDivision of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Science, Niigata, Niigata, Japan.
Hiroyuki NishiyamaDepartment of Urology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Kunihiro YamagataDepartment of Nephrology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Kunitoshi IsekiOkinawa Heart and Renal Association (OHRA), Naha, Okinawa, Japan.
University of Tsukuba · JPIwate Medical University · JPNiigata University · JPUniversity of Miyazaki · JP

Funding

a Japanese Grant-in-Aid for Scientific Research (B) 19H03865Japan Agency for Medical Research and Development JP20ek0310010
6 · The paper itself

Abstract

backgroundDipstick urine tests are a simple and inexpensive method for detecting kidney and urological diseases, such as IgA nephropathy and bladder cancer. The nationwide mass screening program, Specific Health Checkup (SHC), started in Japan in 2008 and targeted all adults between 40 and 74 years of age. Dipstick urine tests for proteinuria and glucosuria are mandatory as part of the SHC, but dipstick urine tests for hematuria are not. However, the dipstick hematuria test is often administered simultaneously with these mandatory tests by some health insurers. Hematuria is common in Japanese general screening participants, particularly elderly women, and the necessity of mass screening using the dipstick hematuria test has been discussed. This study aimed to evaluate the cost-effectiveness of mass screening for dipstick hematuria tests in addition to the SHC.

methodsUsing a decision tree and Markov modeling, we conducted a cost-effectiveness analysis from a Japanese societal perspective.

resultsCompared with the current SHC, mass screening for dipstick hematuria tests, in addition to the SHC, costs less and gains more, which means cost-saving. Similar findings were observed in the sex-specific analysis.

conclusionOur results suggest that mandating the dipstick hematuria test could be justifiable as an efficient use of finite healthcare resources. The results have implications for mass screening programs not only in Japan but worldwide.

Indexed as

HematuriaMass ScreeningAdultAgedCost-Benefit AnalysisFemaleHumansJapanMaleProteinuriaUrinalysisBladder cancerCost-effectivenessDipstick hematuria testIgA nephropathyMass screening

Identifiers

PMID35000032
OpenAlexW4205411765

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.