Evidence map›Paper›PMID 35000001›Full record

ArticleSurgical endoscopy2022

The effect of surgical strategy in difficult cholecystectomy cases on postoperative complications outcome: a value-based healthcare comparative study.

K Cremer, F W H Kloppenberg, J W Vanhommerig, L M Dijksman, N Bode, S C Donkervoort

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

K CremerCollege of Medicine, Erasmus University Rotterdam, Erasmus MC, PO-Box 2040, 3000 CA, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0002-6893-5043
F W H KloppenbergDepartment of Surgery, Treant Zorggroep, PO-Box 30.002, 7800 AA, Emmen, The Netherlands.
J W VanhommerigDepartment of Research and Epidemiology, OLVG, PO-Box 95500, 1090 HM, Amsterdam, The Netherlands.
L M DijksmanDepartment of Value-Based Healthcare, St. Antonius Hospital, PO-Box 2500, 3430 EM, Nieuwegein, The Netherlands.
N BodeDepartment of Surgery, BovenIJ, PO-Box 37610, 1030 BD, Amsterdam, The Netherlands.
S C DonkervoortDepartment of Surgery, OLVG, PO-Box 95500, 1090 HM, Amsterdam, The Netherlands. S.C.Donkervoort@olvg.nl.
OLVG · NLErasmus MC · NLGGD Amsterdam · NLSt. Antonius Ziekenhuis · NLTreant Zorggroep · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn patients undergoing laparoscopic cholecystectomy (LC) for complicated biliary disease, complication rates increase up to 30%. The aim of this study is to assess the effect of differences in surgical strategy comparing outcome data of two large volume hospitals.

methodsA prospective database was created for all the patients who underwent a LC in two large volume hospitals between January 2017 and December 2018. In cases of difficult cholecystectomy in clinic A, regular LC or conversion were surgical strategies. In clinic B, laparoscopic subtotal cholecystectomy was performed as an alternative in difficult cases. The difficulty of the cholecystectomy (score 1-4) and surgical strategy (regular LC, subtotal cholecystectomy, conversion) were scored. Postoperative complications, reinterventions, and ICU admission were assessed. For predicting adverse postoperative complication outcomes, uni- and multivariable analyses were used.

resultsA total of 2104 patients underwent a LC in the study period of which 974 were from clinic A and 1130 were from clinic B. In total, 368 procedures (17%) were scored as a difficult cholecystectomy. In clinic A, more conversions were performed (4.4%) compared to clinic B (1.0%; p < 0.001). In clinic B, more subtotal laparoscopic cholecystectomies were performed (1.8%) compared to clinic A (0%; p =  < 0.001). Overall complication rate was 8.2% for clinic A and 10.2% for clinic B (p = 0.121). Postoperative complication rates per group for regular LC, conversion, and subtotal cholecystectomy in difficult cholecystectomies were 45 (15%), 12 (24%), and 7 (35%; p = 0.035), respectively. The strongest predictor for Clavien-Dindo grade 3-5 complication was subtotal cholecystectomy.

conclusionSurgical strategy in case of a difficult cholecystectomy seems to have an important impact on postoperative complication outcome. The effect of a subtotal cholecystectomy on complications is of great concern.

Indexed as

Cholecystectomy, LaparoscopicGallbladder DiseasesCholecystectomyDelivery of Health CareHumansPostoperative ComplicationsDifficult cholecystectomyLaparoscopic cholecystectomyPostoperative complicationsValue-based healthcare

Identifiers

PMID35000001
OpenAlexW4206491600

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.