Evidence map›Paper›PMID 34999971›Full record

ArticleMikrochimica acta2022

Fabrication of self-assembled peptide nanoparticles for in vitro assessment of cell apoptosis pathway and in vivo therapeutic efficacy.

Syed Faheem Askari Rizvi, Shuai Mu, Chunyan Zhao, Haixia Zhang

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Syed Faheem Askari RizviState Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, Gansu, People's Republic of China.
Shuai MuState Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, Gansu, People's Republic of China.
Chunyan ZhaoSchool of Pharmacy, Lanzhou University, Lanzhou, 730000, Gansu, People's Republic of China.
Haixia ZhangState Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, Gansu, People's Republic of China. Zhanghx@lzu.edu.cn.ORCID http://orcid.org/0000-0002-6927-4662
Lanzhou University · CN

Funding

National Natural Science Foundation of China 21575055
6 · The paper itself

Abstract

Near-infrared fluorescent (NIRF) dye-coupled self-assembled RGD-linked proapoptotic peptide nanoparticles have been synthesized with spherical shape and size ~ 30-40 nm diameters. The peptide sequence was coupled with cyanine 5.5 probe as NIRF-dye to introduce optical imaging properties and pH-dependent method was used to design Cy5.5 coupled self-assembled peptide nanoparticles (f-SAPNs). This nanoprobe has the ability to target α

Indexed as

AnimalsAntineoplastic AgentsApoptosisCell Line, TumorGlioblastomaHumansMaleMiceMice, Inbred BALB CMolecular Docking SimulationNanoparticlesNeoplasms, ExperimentalPeptidesProstatic NeoplasmsProtein ConformationXenograft Model Antitumor AssaysAntineoplastic AgentsPeptidesGlioblastoma multiformeHoming motifNIRF-peptideself-assembled nanoparticles; f-SAPNsα v β 3-integrin

Identifiers

PMID34999971
OpenAlexW4206094579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.