SynthesisInternational journal of epidemiology2022
Reduction in total and major cause-specific mortality from tobacco smoking cessation: a pooled analysis of 16 population-based cohort studies in Asia.
Synthesis in International journal of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Hypertension Canada guideline for the diagnosis and treatment of hypertension in adults in primary care.Canadian family physician Medecin de famille canadien · 2025Guideline
- Guideline
- Hypertension Canada guideline for the diagnosis and treatment of hypertension in adults in primary care.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025Guideline
- The Effectiveness of Smartphone App-Based Interventions for Assisting Smoking Cessation: Systematic Review and Meta-analysis.Journal of medical Internet research · 2023Pooled it
- Guide de pratique clinique en soins de première ligne d'Hypertension Canada pour le diagnostic et le traitement de l'hypertension artérielle chez les adultes.Canadian family physician Medecin de famille canadienGuideline
- Article
- Chronic obstructive pulmonary disease burden attributable to tobacco and the trend change from 1990 to 2021 in China.Tobacco induced diseases · 2025Article
- Tooth loss mediates the association between smoking and an increased risk of dementia among older adults: The JAGES prospective cohort study.Journal of clinical periodontology · 2024Article
- Smoking cessation and mortality risk reduction in older adults with long-term smoking history.BMC public health · 2024Article
- Trends in cigarette smoking and the risk of incident cardiovascular disease among Asian American, Pacific Islander, and multiracial populations.American journal of preventive cardiology · 2024Article
- Effects of smoking cessation on endothelial function as assessed by flow-mediated total dilation.Cardiovascular ultrasound · 2024Article
- Who is at risk of lung nodules on low-dose CT in a Western country? A population-based approach.The European respiratory journal · 2024Article
- Lung Cancer Risk Prediction Models for Asian Ever-Smokers.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2024Article
- Smoking Status and Premature Death Among Japanese Rural Community-Dwelling Persons.Tobacco use insights · 2024Article
- Dose-response risks of all-cause, cancer, and cardiovascular disease mortality according to sex-specific cigarette smoking pack-year quantiles.Tobacco induced diseases · 2024Article
- Association of the age at smoking initiation and cessation on all-cause and cause-specific mortality: The Japan Collaborative Cohort Study.Nagoya journal of medical science · 2023Article
- Current and recent cigarette smoking in relation to cardiovascular and non-cardiovascular mortality in an elderly male Chinese population.Journal of geriatric cardiology : JGC · 2023Article
- Smoking cessation after diagnosis of COPD is associated with lower all-cause and cause-specific mortality: a nationwide population-based cohort study of South Korean men.BMC pulmonary medicine · 2023Article
Corrections and comments
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Authors and funding
25 authors.
Funding
Abstract
backgroundLittle is known about the time course of mortality reduction following smoking cessation in Asians who have smoking behaviours distinct from their Western counterparts. We evaluated the level of reduction in all-cause, cardiovascular disease (CVD) and lung cancer mortality by years since quitting smoking, in Asia.
methodsUsing Cox regression, we analysed individual participant data (n = 709 151) from 16 prospective cohorts conducted in China, Japan, Korea/Singapore, and India/Bangladesh, separately by cohorts. Cohort-specific hazard ratios (HRs) were combined using a random-effects meta-analysis.
resultsDuring a mean follow-up of 12.0 years, 108 287 deaths were ascertained-35 658 from CVD and 7546 from lung cancer. Among Asian men, a dose-response relationship of risk reduction in deaths from all causes, CVD and lung cancer was observed with an increase in years after smoking cessation. Compared with never smokers, however, all-cause and CVD mortality among former smokers remained elevated 10-14 years after quitting [multivariable-adjusted HR (95% confidence interval (CI) = 1.25 (1.13-1.37) and 1.20 (1.02-1.41), respectively]. Lung cancer mortality stayed almost 2-fold higher than among never smokers 15-19 years after smoking cessation [1.97 (1.41-2.73)], particularly among former heavy smokers [2.62 (1.71-4.00)]. Women who quitted for ≥5 years retained a significantly elevated mortality from all causes, CVD and lung cancer. Overall patterns of the cessation-mortality associations were similar across countries.
conclusionsOur findings suggest that adverse effects of tobacco smoking persist for an extended time period, even for more than two decades, which is beyond the time windows defined in current clinical guidelines for risk assessment of lung cancer and CVD.
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