ArticleThe Plant cell2022
Transcriptional repression of TaNOX10 by TaWRKY19 compromises ROS generation and enhances wheat susceptibility to stripe rust.
Article in The Plant cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 102 citations in OpenAlex.
- Transcription factor MdLBD41 negatively regulates resistance to Glomerella leaf spot in apple by suppressing ROS production.The New phytologist · 2026Article
- Functional Characterization of the Oat (International journal of molecular sciences · 2026Article
- The Regulatory Army of Plant Defense: Transcription Factors in the War for Plant Immunity.International journal of molecular sciences · 2026Review
- NbVQ1 physically turns off the NbWRKY45-NbCAT2 module to promote reactive oxygen species burst and disease resistance in plants under high-potassium regime.Plant physiology · 2026Article
- Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance.The plant genome · 2026Review
- A Truncated WRKY Protein Enhances Drought Resistance in Wild Tomatoes Through the SlWRKY16-CIP2b-SlSYP121 Module.Plant biotechnology journal · 2026Article
- ZmWRKY29 Transcriptionally Represses ZmRBOHC to Attenuate ROS Production and Facilitates Gibberella Stalk Rot Susceptibility in Maize.Plant biotechnology journal · 2026Article
- WRKY Transcription Factors: Integral Regulators of Defence Responses to Biotic Stress in Crops.Plant biotechnology journal · 2026Review
- The Maize ZmbHLH118 Transcription Factor Regulates Vacuolar Nitrate Loading by the NOAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The MFS transporter BcTpo1 governs the oxidative stress response and infection of Botrytis cinerea.Crop health · 2026Article
- Protoplast-Based Functional Genomics and Genome Editing: Progress, Challenges and Applications.Plant, cell & environment · 2026Review
- Histone Deacetylase 19 Controls Powdery Mildew Susceptibility by Attenuating Biosynthesis of Cuticular Wax and Salicylic Acid.Journal of fungi (Basel, Switzerland) · 2026Article
- Chemical Priming by Neonicotinoids Unveils CaNEN4 as a Susceptibility Gene Against Phytophthora capsici in Pepper.Molecular plant pathology · 2026Article
- Compartmentalised Function of TaHRC-R Orchestrates ROS Production and Nuclear Condensate Dynamics.Molecular plant pathology · 2026Article
- Auxin accumulation in cereals after infection by Fusarium graminearum: putative biosynthetic pathways and preferences.Stress biology · 2026Review
- Reversible phase dynamics of PsAF5 regulate mitophagy to balance redox levels inScience advances · 2026Article
- Wheat SWI3B Subunit of SWI/SNF Chromatin Remodeling Complex Governs Powdery Mildew Susceptibility by Suppressing Salicylic Acid Biosynthesis.Journal of fungi (Basel, Switzerland) · 2026Article
- Chromatin Remodeler TaSWI3D Controls Wheat Susceptibility to Pathogenic FungusMicroorganisms · 2025Article
- Bioinformatics Analysis of the TomatoPlants (Basel, Switzerland) · 2025Article
- Turning Susceptibility into Strength: A New Era of Durable Resistance in Plants Through Genome Editing.Plants (Basel, Switzerland) · 2025Review
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reactive oxygen species (ROS) are vital for plant immunity and regulation of their production is crucial for plant health. While the mechanisms that elicit ROS production have been relatively well studied, those that repress ROS generation are less well understood. Here, via screening Brachypodium distachyon RNA interference mutants, we identified BdWRKY19 as a negative regulator of ROS generation whose knockdown confers elevated resistance to the rust fungus Puccinia brachypodii. The three wheat paralogous genes TaWRKY19 are induced during infection by virulent P. striiformis f. sp. tritici (Pst) and have partially redundant roles in resistance. The stable overexpression of TaWRKY19 in wheat increased susceptibility to an avirulent Pst race, while mutations in all three TaWRKY19 copies conferred strong resistance to Pst by enhancing host plant ROS accumulation. We show that TaWRKY19 is a transcriptional repressor that binds to a W-box element in the promoter of TaNOX10, which encodes an NADPH oxidase and is required for ROS generation and host resistance to Pst. Collectively, our findings reveal that TaWRKY19 compromises wheat resistance to the fungal pathogen and suggest TaWRKY19 as a potential target to improve wheat resistance to the commercially important wheat stripe rust fungus.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.