Evidence map›Paper›PMID 34999742›Full record

Observational studyAmerican journal of epidemiology2022

Social Distancing in Relation to Severe Exacerbations of Chronic Obstructive Pulmonary Disease: A Nationwide Semi-Experimental Study During the COVID-19 Pandemic.

Mohamad Isam Saeed, Pradeesh Sivapalan, Josefin Eklöf, Charlotte Suppli Ulrik, Andrea Browatzki, Ulla Møller Weinreich, Torben Tranborg Jensen, Tor Biering-Sørensen, Jens-Ulrik Stæhr Jensen

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in American journal of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  8. Article
  9. COPD Phenotyping.Respiratory care · 2023
    Review
  10. Article
  11. What happened to non-SARS-CoV-2 respiratory diseases during the pandemic?Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023
    Article
  12. Article
  13. Hospital Admission Rates in Patients with COPD Throughout the COVID-19 Pandemic.International journal of chronic obstructive pulmonary disease · 2023
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohamad Isam Saeed
Pradeesh Sivapalan
Josefin Eklöf
Charlotte Suppli Ulrik
Andrea Browatzki
Ulla Møller Weinreich
Torben Tranborg Jensen
Tor Biering-Sørensen
Jens-Ulrik Stæhr Jensen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Social distancing measures introduced on March 12, 2020, in Denmark during the COVID-19 pandemic may affect non-COVID-19 admissions for severe acute exacerbation of chronic obstructive pulmonary disease (s-AECOPD). We compared rates of s-AECOPD in a nationwide, observational, semi-experimental cohort study using data from all Danish inhabitants between calendar week 1 through 25 in 2019 and 2020. In a sub-cohort of patients with chronic obstructive pulmonary disease, we examined incidence of s-AECOPD, admissions to an intensive care unit, and all-cause mortality. A total of 3.0 million inhabitants aged ≥40 years, corresponding to 3.0 million person-years, were followed for s-AECOPD. In the social distancing period in 2020, there were 6,212 incidents of s-AECOPD, compared with 11,260 incidents in 2019, resulting in a 45% relative risk reduction. In the cohort with chronic obstructive pulmonary disease (n = 16,675), we observed a lower risk of s-AECOPD in the social distancing period (subdistribution hazard ratio (HR) = 0.34, 95% confidence interval (CI): 0.33, 0.36; absolute risk: 25.4% in 2020 and 42.8% in 2019). The risk of admissions to an intensive care unit was reduced (subdistribution HR = 0.64, 95% CI: 0.47, 0.87), as was all-cause mortality (HR = 0.83, 95% CI: 0.76, 0.90). Overall, the social distancing period was associated with a significant risk reduction for hospital admittance with s-AECOPD.

Indexed as

COVID-19Pulmonary Disease, Chronic ObstructiveCohort StudiesDisease ProgressionHumansPandemicsPhysical Distancingchronic obstructive pulmonary diseaseclinical epidemiologycohort studyCOPD exacerbationsrespiratory infectionssocial distancing

Identifiers

PMID34999742
PMCPMC9383148
OpenAlexW4206727242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.