Evidence map›Paper›PMID 34999622›Full record

ArticleJournal of orthopaedic trauma2022

Risk Factors for Infection and Subsequent Adverse Clinical Results in the Setting of Operatively Treated Pilon Fractures.

Teja Yeramosu, Jibanananda Satpathy, Paul W Perdue, Clarence B Toney, Jesse T Torbert, David J Cinats, Tejas T Patel, Stephen L Kates

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of orthopaedic trauma, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
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  7. Article
  8. Article
  9. Article
  10. Review
  11. The risk of infection in open distal tibial fracture: the DANGER score.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Teja YeramosuVirginia Commonwealth University School of Medicine, Richmond, VA; and.
Jibanananda SatpathyDepartment of Orthopaedic Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA.
Paul W PerdueDepartment of Orthopaedic Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA.
Clarence B ToneyDepartment of Orthopaedic Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA.
Jesse T TorbertDepartment of Orthopaedic Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA.
David J CinatsDepartment of Orthopaedic Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA.
Tejas T PatelDepartment of Orthopaedic Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA.
Stephen L KatesDepartment of Orthopaedic Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA.

Funding

Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
NCATS NIH HHS UL1 TR002649
6 · The paper itself

Abstract

objectiveTo determine patient-specific and injury-specific factors that may predict infection and other adverse clinical results in the setting of tibial pilon fractures.

designRetrospective chart review.

settingLevel 1 academic trauma center. PATIENTS: Two hundred forty-eight patients who underwent operative treatment for tibial pilon fractures between 2010 and 2020.

interventionExternal fixation and/or open reduction and internal fixation. MAIN OUTCOME MEASUREMENTS: Fracture-related infection rates and specific bacteriology, risk factors associated with development of a fracture-related infection, and predictors of adverse clinical results.

resultsTwo hundred forty-eight patients were enrolled. There was an infection rate of 21%. The 3 most common pathogens cultured were methicillin-resistant Staphylococcus aureus (20.3%), Enterobacter cloacae (16.7%), and methicillin-resistant Staphylococcus aureus (15.5%). There was no significant difference in age, sex, race, body mass index, or smoking status between those who developed an infection and those who did not. Patients with diabetes mellitus ( P = 0.0001), open fractures ( P = 0.0043), and comminuted fractures (OTA/AO 43C2 and 43C3) ( P = 0.0065) were more likely to develop a fracture-related infection. The presence of a polymicrobial infection was positively associated with adverse clinical results ( P = 0.006). History of diabetes was also positively associated with adverse results ( P = 0.019).

conclusionsHistory of diabetes and severe fractures, such as those that were open or comminuted fractures, were positively associated with developing a fracture-related infection after the operative fixation of tibial pilon fractures. History of diabetes and presence of a polymicrobial infection were independently associated with adverse clinical results. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

Indexed as

Ankle FracturesCoinfectionFractures, ComminutedFractures, OpenMethicillin-Resistant Staphylococcus aureusTibial FracturesFracture Fixation, InternalHumansRetrospective StudiesRisk FactorsTreatment Outcome

Identifiers

PMID34999622
PMCPMC9253198

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.