Evidence map›Paper›PMID 34999483›Full record

ArticleSexual medicine2022

Establishing a Thermal Imaging Technology (IRT) Based System for Evaluating Rat Erectile Function.

Shuai Liu, Zhendong Zhao, Ziwen Wang, Tongxiang Diao, Keqin Zhang, Hui Zhang, Dingqi Sun, Feng Kong, Qiang Fu

Abstract read
In one paragraph

Article in Sexual medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuai LiuDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, SD, China; Department of Urology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, SD, China.
Zhendong ZhaoDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, SD, China; Department of Urology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, SD, China.
Ziwen WangDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, SD, China.
Tongxiang DiaoDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, SD, China.
Keqin ZhangDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, SD, China.
Hui ZhangDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, SD, China.
Dingqi SunDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, SD, China.
Feng KongDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, SD, China. Electronic address: kongfeng@sdu.edu.com.
Qiang FuDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, SD, China; Department of Urology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, SD, China. Electronic address: qiangfu68@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMeasurement of intra-cavernous pressure (ICP) is an internationally recognized method to evaluate erectile function of animals, however, this process is invasive, destructive, and cannot be repeated, leading to a daunting challenge for monitoring the changes in erectile function throughout the whole treatment duration.

aimTo verify whether infrared ray thermography technology based system could be a good substitution of ICP for evaluating rat erectile function.

methodsA novel thermal image-based method, infrared ray thermography technology (IRT) was employed to monitor erectile function in erectile dysfunction (ED) rats. To detect the sensitivity and specificity of this new technology, 4 ED rat models (Diabetic, nerve-injury, vascular-injury and aged ED models) were established and subjected to both ICP and IRT test. OUTCOMES: Statistical comparisons were done to test the effectiveness of this new way for detecting and dynamically monitoring erectile function.

resultsBased on the data curves obtained from ICP and IRT, the IRT showed a similar trend (including peak value, climbing speed) as that of ICP. IRT is considered as a precise way to monitor the real-time changes of erectile function in all ED rat models. The AUC of peak temperature detected by IRT in DMED, aged ED, vascular-injury ED, the nerve-injury ED and total ED rat models were 0.9811,0.9836,0.9893,0.9989 and 0.9882, respectively. Meanwhile, the AUC of temperature climbing rate were 0.6486,0.8357,0.9184,0.8675and 0.8168.Also,it is a non-invasive process of dynamically monitoring erectile function of a same rat at different time points (before and after drug intervention). The data showed that the real-time recovery by tadalafil was obtained by IRT methods even after treatment for only 2 weeks in the diabetic ED (DMED) rat model.

conclusionA novel noninvasive method for monitoring erectile function in rat ED models was established, and can replace or supplement ICP test. Liu S, Zhao Z, Wang Z et al. Establishing a Thermal Imaging Technology (IRT) Based System for Evaluating Rat Erectile Function. Sex Med 2022;10:100475.

Indexed as

Erectile DysfunctionInfrared Ray Thermography TechnologyIntra-Cavernous Pressure

Identifiers

PMID34999483
PMCPMC8847846

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.