Evidence map›Paper›PMID 34999316›Full record

ReviewWater research2022

Tenets of a holistic approach to drinking water-associated pathogen research, management, and communication.

Caitlin Proctor, Emily Garner, Kerry A Hamilton, Nicholas J Ashbolt, Lindsay J Caverly, Joseph O Falkinham, Charles N Haas, Michele Prevost, D Rebecca Prevots, Amy Pruden and 3 more

Abstract readReview
In one paragraph

Review in Water research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. The effects of silver nitrate onFrontiers in public health · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Water Quality Trade-offs for Risk Management Interventions in a Green Building.Environmental science : water research & technology · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Caitlin ProctorDepartment of Agricultural and Biological Engineering, Division of Environmental and Ecological Engineering, Purdue University, West Lafayette, IN, USA.
Emily GarnerWadsworth Department of Civil & Environmental Engineering, West Virginia University, Morgantown, WV, USA.
Kerry A HamiltonSchool of Sustainable Engineering and the Built Environment and The Biodesign Centre for Environmental Health Engineering, Arizona State University, Tempe, AZ, USA.
Nicholas J AshboltFaculty of Science and Engineering, Southern Cross University, Gold Coast. Queensland, Australia.
Lindsay J CaverlyDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Joseph O FalkinhamDepartment of Biological Sciences, Virginia Tech, Blacksburg, VA, USA.
Charles N HaasDepartment of Civil, Architectural & Environmental Engineering, Drexel University, Philadelphia, PA, USA.
Michele PrevostDepartment of Civil, Geological and Mining Engineering, Polytechnique Montreal, Montreal, Quebec, Canada.
D Rebecca PrevotsEpidemiology Unit, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Amy PrudenDepartment of Civil & Environmental Engineering, Virginia Tech, Blacksburg, VA USA.
Lutgarde RaskinDepartment of Civil & Environmental Engineering, University of Michigan, Ann Arbor, MI, USA.
Janet StoutDepartment of Civil & Environmental Engineering, University of Pittsburgh, and Special Pathogens Laboratory, Pittsburgh, PA, USA.
Sarah-Jane HaigDepartment of Civil & Environmental Engineering, and Department of Environmental & Occupational Health, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: sjhaig@pitt.edu.

Funding

Epidemiology of Mycobacterial InfectionsZIAAI001035 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI PREVOTS, D. REBECCA · 2009 to 2025
$11.6M
Intramural NIH HHS ZIA AI001035
6 · The paper itself

Abstract

In recent years, drinking water-associated pathogens that can cause infections in immunocompromised or otherwise susceptible individuals (henceforth referred to as DWPI), sometimes referred to as opportunistic pathogens or opportunistic premise plumbing pathogens, have received considerable attention. DWPI research has largely been conducted by experts focusing on specific microorganisms or within silos of expertise. The resulting mitigation approaches optimized for a single microorganism may have unintended consequences and trade-offs for other DWPI or other interests (e.g., energy costs and conservation). For example, the ecological and epidemiological issues characteristic of Legionella pneumophila diverge from those relevant for Mycobacterium avium and other nontuberculous mycobacteria. Recent advances in understanding DWPI as part of a complex microbial ecosystem inhabiting drinking water systems continues to reveal additional challenges: namely, how can all microorganisms of concern be managed simultaneously? In order to protect public health, we must take a more holistic approach in all aspects of the field, including basic research, monitoring methods, risk-based mitigation techniques, and policy. A holistic approach will (i) target multiple microorganisms simultaneously, (ii) involve experts across several disciplines, and (iii) communicate results across disciplines and more broadly, proactively addressing source water-to-customer system management.

Indexed as

Drinking WaterLegionella pneumophilaCommunicationEcosystemHumansSanitary EngineeringWater MicrobiologyWater SupplyDrinking WaterBuilding plumbingDrinking waterLegionellanontuberculous mycobacteriaOpportunistic premise plumbing pathogens (OPPs)Pathogens

Identifiers

PMID34999316
PMCPMC8821414

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.