ArticleDental materials : official publication of the Academy of Dental Materials2022
Proanthocyanidin encapsulation for sustained bioactivity in dentin bioadhesion: A two-year study.
Article in Dental materials : official publication of the Academy of Dental Materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Long-term nano-dynamic mechanical analysis and micro-permeability of adhesive interface components using four AB-type proanthocyanidin neutral primers.Journal of dentistry · 2026Article
- Advanced biomechanics and stability of the resin-dentin complex via modular A- and B-type proanthocyanidins.Biomaterials · 2026Article
- Optimization of dental adhesive interfaces using tissue biomodulation with DESIGNER biopolymers.Dental materials : official publication of the Academy of Dental Materials · 2025Article
- A dual action approach of B-type proanthocyanidins for silencing enzymatic activity and sealing natural caries-affected dentin-resin interfaces.Journal of dentistry · 2025Article
- Mechanistic study of the stabilization of dentin-bonded restorative interfaces via collagen reinforcement by multi-acrylamides.Dental materials : official publication of the Academy of Dental Materials · 2024Article
- Development of Proanthocyanidin-Loaded Mesoporous Silica Nanoparticles for Improving Dental Adhesion.Molecular pharmaceutics · 2022Article
- Biodegradation of Dental Resin-Based Composite-A Potential Factor Affecting the Bonding Effect: A Narrative Review.Biomedicines · 2022Review
- Comparison of Proanthocyanidin and EDTA in Enhancing Shear Bond Strength of Giomer and Cention N to Human Dentin: AnJournal of International Society of Preventive & Community DentistryArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesTo determine the long-term effect on the stability of dentin-resin interfaces after the addition of polylactide (PLA) capsules containing proanthocyanidin (PAC) to adhesive resin.
methodsSub-micron (SM) and micron (M) size capsules containing PACs were produced using a combination of emulsification and solvent evaporation techniques and characterized. Human dentin surfaces (n = 8) were etched (35% glycolic acid) and primed (15% enriched Vitis vinifera extract solution - VV
resultsPolydisperse capsules were manufactured with average diameter of 0.36 µm and 1.08 µm for SM and M, respectively. The addition of capsules did not affect TBS (p = 0.889). After 2 years, TBS significantly decreased in SM (p = 0.006), whereas M showed similar initial values (p = 0.291). Overall, less micro-permeability was found in M than the control and SM group (p < 0.001). After 2 years, fractured surfaces from capsule-containing groups failed within the adhesive layer while control fractured at the bottom of the hybrid layer. SIGNIFICANCE: The addition of PAC-filled PLA microcapsules in a dental adhesive did not affect the bond strength while increased and sustained the protection against micro-permeability in the interface, likely due to release of PACs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.