ArticleNeuron2022
A novel reticular node in the brainstem synchronizes neonatal mouse crying with breathing.
Article in Neuron, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Convergent and divergent neural circuit architectures that support acoustic communication.Frontiers in neural circuits · 2022Pooled it
- A distinct vagus-beta cell neural circuit senses glucose and modulates insulin secretion.Molecular metabolism · 2026Article
- Maternal exposure to titanium dioxide nanoparticles disrupts ultrasonic vocalization development in mouse offspring.Particle and fibre toxicology · 2026Article
- A neural circuit for context-dependent multimodal signaling in Drosophila.Nature communications · 2025Article
- An inspiration-off attractor supports the robust and flexible control of breathing.bioRxiv : the preprint server for biology · 2025Article
- Oscillatory brain indexes of auditory-induced predictions about contingences during vocalizations.Experimental brain research · 2025Article
- Endogenous opioids and the development of the mammalian respiratory control network.American journal of physiology. Lung cellular and molecular physiology · 2025Review
- A humanized NOVA1 splicing factor alters mouse vocal communications.Nature communications · 2025Article
- The ultrasonic vocalization (USV) syllable profile during neonatal opioid withdrawal and a kappa opioid receptor component to increased USV emissions in female mice.Psychopharmacology · 2025Article
- The multifunctionality of the brainstem breathing control circuit.Current opinion in neurobiology · 2025Review
- A brainstem map of orofacial rhythms.bioRxiv : the preprint server for biology · 2025Article
- Afferent and Efferent Connections of the Postinspiratory Complex (PiCo) Revealed by AAV and Monosynaptic Rabies Viral Tracing.The Journal of comparative neurology · 2024Article
- The ultrasonic vocalization (USV) syllable profile during neonatal opioid withdrawal and a kappa opioid receptor component to increased USV emissions in female mice.bioRxiv : the preprint server for biology · 2024Article
- Article
- Neuropeptide Modulation Enables Biphasic Internetwork Coordination via a Dual-Network Neuron.eNeuro · 2024Article
- The breath shape controls intonation of mouse vocalizations.bioRxiv : the preprint server for biology · 2024Article
- Brainstem control of vocalization and its coordination with respiration.Science (New York, N.Y.) · 2024Article
- Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping.Nature neuroscience · 2024Article
- A brainstem circuit for phonation and volume control in mice.Nature neuroscience · 2023Article
- Role of NaCell reports · 2023Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Human speech can be divided into short, rhythmically timed elements, similar to syllables within words. Even our cries and laughs, as well as the vocalizations of other species, are periodic. However, the cellular and molecular mechanisms underlying the tempo of mammalian vocalizations remain unknown. Furthermore, even the core cells that produce vocalizations remain ill-defined. Here, we describe rhythmically timed neonatal mouse vocalizations that occur within single breaths and identify a brainstem node that is necessary for and sufficient to structure these cries, which we name the intermediate reticular oscillator (iRO). We show that the iRO acts autonomously and sends direct inputs to key muscles and the respiratory rhythm generator in order to coordinate neonatal vocalizations with breathing, as well as paces and patterns these cries. These results reveal that a novel mammalian brainstem oscillator embedded within the conserved breathing circuitry plays a central role in the production of neonatal vocalizations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.