Evidence map›Paper›PMID 34998468›Full record

ArticleCell reports2022

C2cd6-encoded CatSperτ targets sperm calcium channel to Ca

Jae Yeon Hwang, Huafeng Wang, Yonggang Lu, Masahito Ikawa, Jean-Ju Chung

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Molecular basis of the higher-order assembly of CatSper.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Dynamic relocation of PKA regulatory subunits during sperm capacitation: Linking PKA to the CatSper signaling complex.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Intracellular MgFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  16. Review
  17. Article
  18. CaAnimal cells and systems · 2024
    Review
  19. Analysis of CaFrontiers in cell and developmental biology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jae Yeon HwangDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA.
Huafeng WangDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA.
Yonggang LuResearch Institute for Microbial Diseases, Osaka University, Suita, Osaka 5650871, Japan.
Masahito IkawaResearch Institute for Microbial Diseases, Osaka University, Suita, Osaka 5650871, Japan.
Jean-Ju ChungDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA; Department of Gynecology and Obstetrics, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address: jean-ju.chung@yale.edu.
Yale University · USThe University of Osaka · JP

Funding

Targeting sperm-specific proteins during meiosis and sperm morphogenesisP01HD087157 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MATZUK, MARTIN M. · 2017 to 2021
$6.2M
Functional analysis of novel testis-expressed secreted and transmembrane proteinsR01HD088412 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MARTIN M. MATZUK · 2016 to 2026
$4.5M
CatSper regulation of sperm physiology and fertilityR01HD096745 · NICHD · YALE UNIVERSITY · PI Jean-Ju Lucia Chung · 2019 to 2026
$3.4M
NICHD NIH HHS P01 HD087157NICHD NIH HHS R01 HD088412NICHD NIH HHS R01 HD096745
6 · The paper itself

Abstract

In mammalian sperm cells, regulation of spatiotemporal Ca

Indexed as

AnimalsCalcium ChannelsCalcium SignalingFlagellaMaleMiceProtein TransportSpermatozoaSperm MotilityCalcium ChannelsCatsper1 protein, mouseCa(2+) channelCa(2+) signalingCatSperdomain organizationflagellar membrane targetingmale fertilitysperm motility

Identifiers

PMID34998468
PMCPMC8857959
OpenAlexW4206824884

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.