ArticleDrug and alcohol dependence2022
Alcohol craving and withdrawal at treatment entry prospectively predict alcohol use outcomes during outpatient treatment.
Article in Drug and alcohol dependence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 43 citations in OpenAlex.
- Effects of the neuroactive steroid precursor pregnenolone on stress- and alcohol cue-provoked pain responses in individuals with alcohol use disorder.Experimental and clinical psychopharmacology · 2026Trial
- Variations in alcohol craving and negative mood during a clinical trial of ibudilast for alcohol use disorder.Alcohol, clinical & experimental research · 2025Trial
- Pregnenolone effects on provoked alcohol craving, anxiety, HPA axis, and autonomic arousal in individuals with alcohol use disorder.Psychopharmacology · 2023Trial
- Prazosin-Related Reductions in Daily Craving Mediate Treatment-Related Daily Alcohol Use Outcomes in Alcohol Use Disorder.Biological psychiatry global open science · 2026Article
- Does treatment status matter? An examination of daily approach and avoidance inclinations predicting drinking in individuals diagnosed with alcohol use disorder.Drug and alcohol dependence · 2026Article
- Alterations in glucose and insulin resistance following stress and alcohol cues predict alcohol craving in those with AUD and obesity: A preliminary study.Alcohol, clinical & experimental research · 2026 · on this mapArticle
- Early alcohol abstinence symptoms and the role of cumulative adversity.Alcohol, clinical & experimental research · 2025Article
- Grouping motivational interviewing for alcohol craving in individuals with alcohol use disorder: the influence of drinking history on its efficacy.European archives of psychiatry and clinical neuroscience · 2025Article
- Examining the moderating role of intolerance of uncertainty on pain tolerance and craving in patients with chronic pain and alcohol use disorder.Alcohol (Fayetteville, N.Y.) · 2025Article
- The moderating role of trait impulsivity on reward sensitivity and alcohol craving.Addictive behaviors · 2025Article
- Clinical Characteristics and Treatment Outcomes of Alcohol Withdrawal Syndrome in Adolescents and Young Adults.JAACAP open · 2025Article
- Network state dynamics underpin basal craving in a transdiagnostic population.Molecular psychiatry · 2025Article
- Facial expression analysis and machine learning for objective assessment of alcohol craving in alcohol use disorder: a study protocol.Frontiers in psychiatry · 2025Article
- Laboratory and Real-World Experimental Approaches to Understanding Alcohol Relapse.Current topics in behavioral neurosciences · 2025Review
- Affiliation to the Alcoholics Anonymous (AA) community: A qualitative study on differences between highly affiliated and low/non-affiliated individuals.Nordisk alkohol- & narkotikatidskrift : NAT · 2024Article
- Neural responses to stress and alcohol cues in individuals with pain with and without alcohol use disorder.Addiction biology · 2024Article
- Sweet Taste Preference as a Moderator of Links Between Internalizing Symptoms and Alcohol Craving.Journal of studies on alcohol and drugs · 2024Article
- Effect of N-acetylcysteine on neural alcohol cue reactivity and craving in adolescents who drink heavily: A preliminary randomized clinical trial.Alcohol, clinical & experimental research · 2024Article
- Stress and substance use disorders: risk, relapse, and treatment outcomes.The Journal of clinical investigation · 2024Review
- Evidence that personalized racial stress procedures elicit a stress response and increases alcohol craving among Black adults with alcohol use disorder: A laboratory pilot study.Drug and alcohol dependence · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveChronic alcohol use increases risk of alcohol craving and withdrawal symptoms (AW) as well as abstinence-related distress symptoms, in those entering alcohol use disorder (AUD) treatment. Here, we examined whether AW and alcohol craving in AUD patients entering outpatient treatment prospectively predicts future heavy drinking days/week (HDD) and additional alcohol use outcomes during 8-weeks of outpatient treatment, and their relationship to abstinence symptoms of depression, anxiety and sleep difficulties.
methodsParticipants were 80 treatment-seeking adults with current DSM-5 AUD (39% female; 43% White; 20-60 years) who completed assessments of AW and alcohol craving and also alcohol abstinence symptoms of depression, anxiety, and sleep quality at treatment intake. Participants were prospectively followed using daily diaries for alcohol intake during 8-week of standardized weekly relapse prevention counseling to support recovery.
resultsAfter accounting for demographic and pre-treatment alcohol use, greater alcohol craving at treatment entry predicted higher HDD (p < .013) as well as greater drinking days (DD: p < .004), average drinks per drinking day/week (AvgD: p < .001) and relapse to heavy drinking (p < .05), while higher levels of pretreatment AW symptoms interacted with treatment week to predict greater HDD (p < .018). Abstinence symptoms of depression, anxiety, and sleep difficulties were associated with craving and AW but did not predict any drinking-related outcomes.
conclusionsThese results provide evidence that increased alcohol craving and AW may serve as prognostic indicators of greater risk of heavy drinking in outpatient treatment. Findings suggest the need to evaluate craving and AW at outpatient treatment entry and develop targeted treatments to specifically address the effects of craving and AW on drinking outcomes in outpatient AUD treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.