Evidence map›Paper›PMID 34998253›Full record

Trial reportDrug and alcohol dependence2022

Cognitive training in recently-abstinent individuals with alcohol use disorder improves emotional stroop performance: Evidence from a randomized pilot trial.

Ben Lewis, Christian C Garcia, Julianne L Price, Susanne Schweizer, Sara Jo Nixon

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Alcohol Use Disorder and Dementia: A Review.Alcohol research : current reviews · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Ben LewisUniversity of Florida, Department of Psychiatry, Gainesville, FL, United States; University of Florida, Department of Psychology, Gainesville, FL, United States; University of Florida, Center for Addiction Research & Education, Gainesville, FL, United States. Electronic address: benlewis@ufl.edu.
Christian C GarciaUniversity of Florida, Department of Psychiatry, Gainesville, FL, United States; University of Florida, Department of Psychology, Gainesville, FL, United States; University of Florida, Center for Addiction Research & Education, Gainesville, FL, United States.
Julianne L PriceRutgers University, Center of Alcohol & Substance Use Studies, New Brunswick, NJ, United States.
Susanne SchweizerUniversity of Cambridge, Department of Psychology, Cambridge, UK; University of New South Wales, School of Psychology, Sydney, Australia.
Sara Jo NixonUniversity of Florida, Department of Psychiatry, Gainesville, FL, United States; University of Florida, Department of Psychology, Gainesville, FL, United States; University of Florida, Center for Addiction Research & Education, Gainesville, FL, United States.
University of Florida · USRutgers, The State University of New Jersey · USUNSW Sydney · AU

Funding

Enhancing Recovery Outcomes in Alcohol Use Disorder: Cognitive Training as an Adjunct to TreatmentK01AA026893 · NIAAA · UNIVERSITY OF FLORIDA · PI LEWIS, BEN · 2018 to 2022
$729k
Sex Differences, Cognitive Training & Emotion Processing: A pilot study of Treatment-Seeking Men and Women with Alcohol Use DisorderR03AA025430 · NIAAA · UNIVERSITY OF FLORIDA · PI NIXON, SARA JO · 2017 to 2018
$153k
NIAAA NIH HHS K01 AA026893NIAAA NIH HHS R03 AA025430
6 · The paper itself

Abstract

backgroundCognitive training interventions appear capable of improving alcohol-associated neurobehavioral deficits in recently detoxified individuals. However, efficacy remains incompletely characterized in alcohol use disorder (AUD) and available data address only non-affective cognitive outcomes; enhancement of social cognition remains uninvestigated. We utilized a training paradigm in which successfully ignoring emotionally-valent stimuli benefitted task performance. We hypothesized trained individuals would display improvements in an affective inhibitory control task, and that individuals trained with high valence (relative to neutral) stimuli would evince greater improvement.

methods42 recently detoxified inpatients with AUD were assigned to one of three groups (Emotional Training, Neutral Training, or Treatment as Usual [TAU]). Training consisted of two computerized working memory tasks (dual-modality n-back task; attend/ignore task) which included task-irrelevant stimuli (emotional vs. neutral). Post-training performance efficiency (indexing speed-accuracy tradeoffs) in an emotional Stroop task was the outcome of interest.

resultsSignificant group by time interactions were detected for emotional Stroop performance, supporting our hypothesis that trained groups would exhibit greater improvement than TAU controls (F[2,39]=8.61, p < .01). Additionally, the emotional training condition appeared to result in greater improvement relative to neutral training (F[1,26]=4.98, p < .01).

conclusionResults are consistent with current literature suggesting the potential of training to enhance cognitive recovery in early abstinence. Findings inform the development of training protocols, suggesting integration of task-irrelevant distractor stimuli in training may enhance cognitive control outcomes. Further, they expand the relevant domains for application of training approaches, providing novel evidence that among individuals with AUD, training-associated benefits may extend to social cognitive domains.

Indexed as

AlcoholismCognition DisordersCognitionEmotionsHumansPilot ProjectsAlcoholAlcohol use disorderCognitionCognitive trainingEmotion processingTreatment

Identifiers

PMID34998253
PMCPMC9311324
OpenAlexW4200505445

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.