ArticleArchives of gerontology and geriatrics
Association between sarcopenia and erectile dysfunction in older males.
Article in Archives of gerontology and geriatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Circulating biomarkers in older adults with and without sarcopenia: a systematic review and meta-analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Pooled it
- Sarcopenia-related traits and erectile dysfunction: a bi-directional Mendelian randomization study.Sexual medicine · 2026Article
- Using a two sample Mendelian randomization approach to explore the causal relationship between erectile dysfunction and lung function.Translational andrology and urology · 2024Article
- Development and validation of a prediction model for ED using machine learning: according to NHANES 2001-2004.Scientific reports · 2024Article
- Impact of sarcopenia and vitamin D levels on the severity of lower urinary tract symptoms in older males.Saudi medical journal · 2024Article
- Is erectile dysfunction associated with osteoarthritis and rheumatoid arthritis? Insights from a population-based study.Sexual medicine · 2024Article
- Muscle Strength and Male Sexual Function.Journal of clinical medicine · 2024Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIn advanced age, both sarcopenia and erectile dysfunction (ED) occur with similar underlying causes through different mechanisms. In our study we investigated the association between sarcopenia and ED in older men.
methodsA total of 193 male patients aged 60 years and older were included in the study. The presence of sarcopenia was investigated in accordance with EWGSOP2 diagnostic criteria. For evaluation of ED, we used the 5-question International Index of Erectile Dysfunction questionnaire with categories of no ED, mild-moderate ED, and moderate-severe ED. Total testosterone levels were measured.
resultsThe median age of the patients was 71.9 (range 60-93 years). The prevalence of sarcopenia was 24.9%, and moderate-severe ED was 49.2%. Moderate-severe ED was more common in patients with sarcopenia than those without (70.8% vs 42.1%, p < 0.001). After adjustment for age and Charlson Comorbidity Index, the presence of sarcopenia was significantly associated with moderate-severe ED with odds ratio (OR) of 2.71 (95% Confidence Interval [CI] 1.29-5.73, p = 0.009). The components of sarcopenia were assessed separately in multivariate analysis. Muscle strength and muscle mass were significantly associated with moderate-severe ED with OR of 0.93 (95%CI 0.89-0.98) and 0.68 (95%CI 0.54-0.86), respectively, whereas gait speed was not associated with moderate-severe ED.
conclusionThe presence of sarcopenia in older men is associated with an increased risk of moderate-severe ED. In addition, decreased muscle strength and decreased muscle mass are associated with an increased risk of moderate-severe ED. Prospective studies are needed to reveal the causality between sarcopenia and ED.
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