Evidence map›Paper›PMID 34997877›Full record

SynthesisClinical autonomic research : official journal of the Clinical Autonomic Research Society2022

The role of central autonomic nervous system dysfunction in Takotsubo syndrome: a systematic review.

Vojtech Brazdil, Petr Kala, Martin Hudec, Martin Poloczek, Jan Kanovsky, Roman Stipal, Petr Jerabek, Otakar Bocek, Martin Pail, Milan Brazdil

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Takotsubo syndrome linked to paroxysmal sympathetic hyperactivity as a postoperative complication after brain tumor removal: a case report and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Review
  5. Perioperative management of Takotsubo cardiomyopathy: an overview.Journal of anesthesia, analgesia and critical care · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Vojtech Brazdil *Department of Internal Medicine and Cardiology, University Hospital Brno, Brno, Czech Republic.
Petr Kala *Department of Internal Medicine and Cardiology, University Hospital Brno, Brno, Czech Republic. Kala.Petr@fnbrno.cz.ORCID 0000-0002-4416-9065
Martin HudecDepartment of Internal Medicine and Cardiology, University Hospital Brno, Brno, Czech Republic.
Martin PoloczekDepartment of Internal Medicine and Cardiology, University Hospital Brno, Brno, Czech Republic.
Jan KanovskyDepartment of Internal Medicine and Cardiology, University Hospital Brno, Brno, Czech Republic.
Roman StipalDepartment of Internal Medicine and Cardiology, University Hospital Brno, Brno, Czech Republic.
Petr JerabekDepartment of Internal Medicine and Cardiology, University Hospital Brno, Brno, Czech Republic.
Otakar BocekDepartment of Internal Medicine and Cardiology, University Hospital Brno, Brno, Czech Republic.
Martin PailFaculty of Medicine, Masaryk University, Brno, Czech Republic.
Milan BrazdilFaculty of Medicine, Masaryk University, Brno, Czech Republic.
Masaryk University · CZUniversity Hospital Brno · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTakotsubo syndrome (TTS), also known as stress cardiomyopathy or "broken heart" syndrome, is a mysterious condition that often mimics an acute myocardial infarction. Both are characterized by left ventricular systolic dysfunction. However, this dysfunction is reversible in the majority of TTS patients. PURPOSE: Recent studies surprisingly demonstrated that TTS, initially perceived as a benign condition, has a long-term prognosis akin to myocardial infarction. Therefore, the health consequences and societal impact of TTS are not trivial. The pathophysiological mechanisms of TTS are not yet completely understood. In the last decade, attention has been increasingly focused on the putative role of the central nervous system in the pathogenesis of TTS.

conclusionIn this review, we aim to summarize the state of the art in the field of the brain-heart axis, regional structural and functional brain abnormalities, and connectivity aberrancies in TTS.

Indexed as

Takotsubo CardiomyopathyAutonomic Nervous SystemBrainHumansPrognosisAmygdalaBrain connectivityBrain–heart axisInsular cortexTakotsubo syndrome

Identifiers

PMID34997877
PMCPMC8898237
OpenAlexW4205684667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.